1 Result for "

Zincov

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Zincov" in MCE Product Catalog:

Cat. No.: HY-183878
CAS No.: 71431-46-4
Target:  

Bacterial

Research Areas:  

Infection Metabolic Disease

Zincov is an orally active hydroxamic acid derivative and bacterial metalloproteinase inhibitor. Zincov blocks chloride ion binding by binding to the active site of thermolysin, thereby inhibiting the hydrolysis and blood coagulation reactions catalyzed by this enzyme. Meanwhile, Zincov attenuates cytotoxicity, prevents protein degradation and ZO-1 rearrangement without affecting the functions of other common proteases. Zincov exhibits blood glucose-regulating and antioxidant activities; it reduces blood glucose levels and increases liver dry weight in diabetic rats, but elevates blood glucose levels in normal rats. Zincov is widely used in studies related to cholera and diabetes .
loading...
    loading...