3 Results for "

abscopal suppression

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "abscopal suppression" in MCE Product Catalog:

Cat. No.: HY-183597A
Target:  

Drug Derivative

Research Areas:  

Cancer

L-BPA-BPA hydrochloride is an aromatic dipeptide and an analog of L-BPA (HY-W087830). L-BPA-BPA hydrochloride undergoes rapid hydrolytic cleavage in vivo to release the boron neutron capture agent L-BPA. L-BPA-BPA hydrochloride enables boron delivery to tumors; when used in combination with neutron irradiation, it also induces immunological effects including vaccine responses and abscopal tumor suppression. L-BPA-BPA hydrochloride can be used in the research of colon cancer and hypopharyngeal cancer .
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Cat. No.: HY-183597
CAS No.: 2941355-30-0
Target:  

Drug Derivative

Research Areas:  

Cancer

L-BPA-BPA is an aromatic dipeptide and an analog of L-BPA (HY-W087830). L-BPA-BPA undergoes rapid hydrolytic cleavage in vivo to release the boron neutron capture agent L-BPA. L-BPA-BPA enables boron delivery to tumors; when used in combination with neutron irradiation, it also induces immunological effects including vaccine responses and abscopal tumor suppression. L-BPA-BPA can be used in the research of colon cancer and hypopharyngeal cancer .
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Cat. No.: HY-183596
CAS No.: 2941355-21-9
Target:  

Drug Intermediate

Research Areas:  

Cancer

L-His-BPA is a prodrug of L-p-Boronophenylalanine (L-BPA) (HY-W087830), formed by the peptide bond linkage of L-histidine (L-His) (HY-N0832) and L-BPA. L-His-BPA is rapidly cleaved by endogenous proteases to de novo release L-BPA in the systemic circulation. When used in combination with neutron irradiation, L-His-BPA induces complete and durable tumor regression, elicits cancer vaccine responses, and produces abscopal inhibitory effects on unirradiated distant tumors. L-His-BPA can be used in studies of boron neutron capture therapy (BNCT) for relapsed/advanced solid tumors .
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