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amyloid-binding stain

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

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Fluorescent Dyes

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0404

    Fluorescent Dye Neurological Disease
    Direct Red 254 is a bisazo dye for textile applications. Direct Red 254 can be used for amyloid tissue staining in basic research on neurodegenerative diseases (e.g., Alzheimer's disease) .
    Direct red 254
  • HY-D3192

    Fluorescent Dye Bacterial Amyloid-β Infection
    CDy11 is a fluorescent probe and amyloid-binding dye (λex=590 nm; λem=612 nm), with a Ka of 29 μM for Pseudomonas aeruginosa Fap. CDy11 specifically recognizes amyloid fibrils in bacterial biofilms and exhibits significantly enhanced fluorescence upon binding to the target. CDy11 shows no staining effect on amyloid-deficient mutant strains, planktonic cells or protein monomers. CDy11 supports in vivo imaging of Pseudomonas aeruginosa biofilms in mouse implant and corneal infection models. CDy11 is widely used in studies of Staphylococcus aureus biofilm infections, dental caries, and Pseudomonas aeruginosa-associated implant and corneal infections .
    CDy11

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