3 Results for "

cassane diterpenoids

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "cassane diterpenoids" in MCE Product Catalog:

Cat. No.: HY-N1494
CAS No.: 279683-46-4
Synonyms: 14-Deoxy-ε-caesalpin
Target:  

NO Synthase

Research Areas:  

Inflammation/Immunology

(+)-14-Deoxy-ε-caesalpin (14-Deoxy-ε-caesalpin), a cassane diterpenoid, inhibits nitric oxide (NO) production release of RAW 264.7 cells stimulated by Lipopolysaccharide (LPS) .
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Cat. No.: HY-149523
Research Areas:  

Inflammation/Immunology Cancer

Anticancer agent 157 (compound 15) is a NO inhibitor (IC50=0.62 μg/mL) with anti-inflammatory and anticancer activities. Anticancer agent 157 can bind to iNOS (inducible NO synthase) and caspase 8, causing nuclear fragmentation and chromatin condensation, inducing apoptosis. Anticancer agent 157 inhibits HT29 colon cancer cells (IC50=2.45 μg/mL), Hep-G2 liver cancer cells (IC50=3.25 μg/mL), and B16-F10 murine melanoma cells (IC50=3.84 μg/mL) .
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Cat. No.: HY-N18140
CAS No.: 144161-80-8
Caesaljapin (Compound 4) is a cassane-type diterpenoid that can be isolated from plants of the genus Caesalpinia (Fabaceae) .
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