1 Result for "

cerebrovascular dysfunction

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "cerebrovascular dysfunction" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-125864B
CAS No.: 9001-32-5
Target:  

MMP Cadherin

Murine Fibrinogen is a native fibrinogen derived from mouse plasma. Murine Fibrinogen acts as a cerebrovascular permeability enhancer. Murine Fibrinogen activates matrix metalloproteinase-9 (MMP-9), downregulates the expression of vascular endothelial cadherin (VE-cadherin), and upregulates the expression of plasmalemmal vesicle-associated protein-1 (PV-1). Murine Fibrinogen increases macromolecular leakage from pial veins, thereby disrupting the microvascular integrity of cerebral blood vessels. Murine Fibrinogen can be used in studies related to cerebrovascular dysfunction .
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