2 Results for "

cough reflex pathways

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "cough reflex pathways" in MCE Product Catalog:

Cat. No.: HY-B1032
CAS No.: 17692-31-8
Synonyms: (±)-Dropropizine; UCB-196
Target:  

Histamine Receptor

Research Areas:  

Neurological Disease

Dropropizine ((±)-Dropropizine; UCB-196) is an orally effective, peripherally selective antitussive that inhibits the activity of peripheral receptors and afferent nerves in the respiratory tract. Dropropizine acts on the cough reflex pathway, does not pass the blood-brain barrier, and has no central nervous system side effects. Dropropizine mainly regulates the level of sensory neuropeptides and inhibits the afferent signal transmission of the cough reflex, thereby alleviating the symptoms of dry cough, and has both mild local anesthetic and antihistamine activity. Dropropizine is mainly used for symptomatic research on dry cough caused by respiratory diseases .
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Cat. No.: HY-178450
CAS No.: 2766757-56-4
Target:  

P2X Receptor

Research Areas:  

Neurological Disease

HW091077 is a highly selective P2X3 receptor antagonist with an IC50 of 17 nM. HW091077 blocks ATP-induced calcium influx and cell depolarization to inhibit cough reflex pathways. HW091077 is promising for research of chronic cough .
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