2766757-56-4

HW091077 Chemical Structure
2766757-56-4

Chemical Structure

HW091077

  • CAS No.: 2766757-56-4
  • Formula:C22H22F4N4O3S
  • Molecular Weight:498.49

InChIKey: RILNDXNTTKODDX-AGIUHOORSA-N

SMILES: FC1=C(C2=NC=C(C)S2)C=C(C=C1C(N[C@@H](C3=CN=C(C(F)(F)F)N=C3)C)=O)O[C@@H](C)[C@@H](O)C

Biological Activity: HW091077 is a highly selective P2X3 receptor antagonist with an IC50 of 17 nM. HW091077 blocks ATP-induced calcium influx and cell depolarization to inhibit cough reflex pathways. HW091077 is promising for research of chronic cough[1].

Cat. No. Product Name Purity Description Pricing
HY-178450
HW091077 HW091077 is a highly selective P2X3 receptor antagonist with an IC50 of 17 nM. HW091077 blocks ATP-induced calcium influx and cell depolarization to inhibit cough reflex pathways. HW091077 is promising for research of chronic cough.
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