2 Results for "

guggulsterone+e

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "guggulsterone+e" in MCE Product Catalog:

(-)-(E)-Guggulsterone
(-)-(E)-Guggulsterone
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Cat. No.: HY-N7781
CAS No.: 39025-24-6
Synonyms: (E)-Guggulsterone
Category:  

Commiphora myrrha (Nees) Engl. Metabolic Disease Plants Burseraceae Disease Research Fields Steroids

Target:  

FXR Keap1-Nrf2 Heme Oxygenase (HO) Dengue Virus Bacterial Reactive Oxygen Species (ROS) Estrogen Receptor/ERR Cytochrome P450 Drug Metabolite

(-)-(E)-Guggulsterone ((E)-Guggulsterone) is an orally active natural stereoisomer of Guggulsterone (HY-107738). (-)-(E)-Guggulsterone is an antagonist for the Farnesoid X Receptor (FXR) with an IC50 of 24.06 μM and possesses potent hypolipidemic properties. (-)-(E)-Guggulsterone suppresses dengue virus (DENV) replication by upregulating antiviral interferon responses by inducing HO-1 expression via Nrf2 activation. (-)-(E)-Guggulsterone exhibits antibacterial activities against Bacillus subtilis, Staphylococcus aureus and Pseudomonas aeruginosa. (-)-(E)-Guggulsterone has cardiac protective and antioxidant activities in rats .
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(-)-(E)-Guggulsterone (Standard)
(-)-(E)-Guggulsterone (Standard)
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Cat. No.: HY-N7781R
CAS No.: 39025-24-6
Synonyms: (E)-Guggulsterone (Standard)
Category:  

Commiphora myrrha (Nees) Engl. Metabolic Disease Plants Burseraceae Disease Research Fields Steroids

Target:  

Reference Standards Drug Metabolite FXR Keap1-Nrf2 Heme Oxygenase (HO) Dengue Virus Bacterial Reactive Oxygen Species (ROS) Estrogen Receptor/ERR Cytochrome P450

(-)-(E) -guggulsterone (Standard) is the analytical standard for (-)-(E) -guggulsterone ((E)-Guggulsterone) (HY-N7781). (-)-(E)-Guggulsterone is an orally active natural stereoisomer of Guggulsterone (HY-107738). (-)-(E)-Guggulsterone is an antagonist for the Farnesoid X Receptor (FXR) with an IC50 of 24.06 μM and possesses potent hypolipidemic properties. (-)-(E)-Guggulsterone suppresses dengue virus (DENV) replication by upregulating antiviral interferon responses by inducing HO-1 expression via Nrf2 activation. (-)-(E)-Guggulsterone exhibits antibacterial activities against Bacillus subtilis, Staphylococcus aureus and Pseudomonas aeruginosa. (-)-(E)-Guggulsterone has cardiac protective and antioxidant activities in rats.
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