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(-)-(E)-Guggulsterone (Standard)

(Synonyms: (E)-Guggulsterone (Standard))

(-)-(E) -guggulsterone (Standard) is the analytical standard for (-)-(E) -guggulsterone ((E)-Guggulsterone) (HY-N7781). (-)-(E)-Guggulsterone is an orally active natural stereoisomer of Guggulsterone (HY-107738). (-)-(E)-Guggulsterone is an antagonist for the Farnesoid X Receptor (FXR) with an IC50 of 24.06 μM and possesses potent hypolipidemic properties. (-)-(E)-Guggulsterone suppresses dengue virus (DENV) replication by upregulating antiviral interferon responses by inducing HO-1 expression via Nrf2 activation. (-)-(E)-Guggulsterone exhibits antibacterial activities against Bacillus subtilis, Staphylococcus aureus and Pseudomonas aeruginosa. (-)-(E)-Guggulsterone has cardiac protective and antioxidant activities in rats.

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  • CAS No.: 39025-24-6
  • Formula: C21H28O2
  • Molecular Weight:312.45
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • (-)-(E)-Guggulsterone (Standard) Chemical Structure
    (-)-(E)-Guggulsterone (Standard) Chemical Structure
CAS No.: 39025-24-6
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  • (-)-(E)-Guggulsterone (Standard) Chemical Structure
    (-)-(E)-Guggulsterone (Standard) Chemical Structure
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  • (-)-(E)-Guggulsterone (Standard)