1 Result for "

hTfR1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "hTfR1" in MCE Product Catalog:

Cat. No.: HY-183708
CAS No.: 475595-06-3
Target:  

Arenavirus

Research Areas:  

Infection

Antiviral agent 85 is a broad-spectrum arenavirus entry inhibitor with an EC90 of 0.13 µM against Junín virus (JUNV). Antiviral agent 85 blocks the entry of various arenaviruses through both hTfR1-dependent and hTfR1-independent pathways, acting on the early and early post-entry stages of infection. Antiviral agent 85 exhibits antiviral activity against a variety of arenaviruses, is well tolerated in hTfR1-expressing JUNV-infected mouse models, but fails to provide protective effects. Antiviral agent 85 can be used in studies related to arenavirus hemorrhagic fevers [1].
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