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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
human TOP2A
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "human TOP2A" in MCE Product Catalog:
3
3 Cited Publications
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Research Areas:
PluriSIn #2 is a selective transcriptional inhibitor of topoisomerase II α (TOP2A). PluriSIn #2 is a compound that selectively eliminates undifferentiated human pluripotent stem cells (hPSCs) .
Cat. No.: HY-RS14894
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TOP2A Human Pre-designed siRNA Set A contains three designed siRNAs for TOP2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P704742
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TOP2A; DNA TOPoisomerase 2-alpha; TOP2; DNA TOPoisomerase II; alpha isozyme
Cat. No.: HY-P85929
Synonyms: alpha isozyme; ATP hydrolyzing DNA TOPoisomerase II alfa; DNA gyrase; DNA TOPoisomerase; ATP hydrolyzing; DNA TOPoisomerase 2 alpha; DNA TOPoisomerase 2-alpha; DNA TOPoisomerase II 170 kD; DNA TOPoisomerase II alpha isozyme; DNA TOPoisomerase II; DNA TOPoisomerase2; TOP 2A; TOP2; TOP2A; TOP2A_human; TOPoisomerase DNA II alpha 170 kDa; TP2A
Cat. No.: HY-W654323
CAS No.: 2468637-62-7
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Research Areas:
PNU-142586 sodiu) is the major metabolite of Linezolid (HY-10394). PNU-142586 can inhibit the activity of DNA topoisomerase 2-α (TOP2A) and DNA topoisomerase 2-β (TOP2B). PNU-142586 interferes with DNA replication and transcription by blocking the binding of DNA to TOP2 and inhibiting ATP hydrolysis, ultimately leading to antiproliferative and cytotoxic effects, including mitochondrial dysfunction. PNU-142586 can be used to study Linezolid-induced hematotoxicity and its molecular mechanism .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
