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human thyroid stimulating hormone

" in MedChemExpress (MCE) Product Catalog:

By Targets:	TSH Receptor (1) Fluorescent Dye (1) PKA (1)
By Research Areas:	Inflammation/Immunology (1) Metabolic Disease (1)

Inhibitors & Agonists

Fluorescent Dyes

Inhibitory Antibodies

Antibodies

Targets Recommended: TSH Receptor Thyroid Hormone Receptor PTHR GHR c-Fms Nuclear Hormone Receptor 4A/NR4A MCHR1 (GPR24) GHSR Hormone-Sensitive Lipase (HSL) GnRH Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P991202

Anti-TSHR Antibody (M22)	TSH Receptor PKA	Metabolic Disease Inflammation/Immunology
Anti-TSHR Antibody (M22) is a selective agonist targeting TSHR (thyroid-stimulating hormone receptor), acting through competitive binding to the extracellular domain of TSHR. Anti-TSHR Antibody (M22) can mimic the biological effects of thyroid-stimulating hormone (TSH), activating downstream cAMP-PKA and other signaling pathways. Anti-TSHR Antibody (M22) can stimulate the proliferation of thyroid follicular epithelial cells and human umbilical vein endothelial cells (HUVECs), promote angiogenesis and tube formation, cell migration, and also upregulate the expression of angiogenesis-related proteins such as PROX1. Anti-TSHR Antibody (M22) can be used in research areas such as the mechanisms of goiter formation in Graves' disease (GD), angiogenesis regulation, and TSHR antagonist screening .

HY-D2468

HRP-Streptavidin 1 Publications Verification	Fluorescent Dye	Others
Sulfonylurea Receptor HRP-Streptavidin is a biotin-binding signal amplifier designed to bind tightly with biotinylated anti-TSH monoclonal antibodies, thereby constituting a key component of the signal amplification system in immunoassays. HRP-Streptavidin is formed by the covalent coupling of Horseradish Peroxidase (HRP) with Streptavidin; it combines the highly efficient catalytic activity of the enzyme with the high affinity of Streptavidin for biotin, making it a potent and sensitive tool for signal amplification. HRP-Streptavidin is suitable for use in Western Blotting, ELISA, and other detection techniques .

Cat. No.	Product Name	Type

HY-D2468

HRP-Streptavidin 1 Publications Verification	Fluorescent Dyes
Sulfonylurea Receptor HRP-Streptavidin is a biotin-binding signal amplifier designed to bind tightly with biotinylated anti-TSH monoclonal antibodies, thereby constituting a key component of the signal amplification system in immunoassays. HRP-Streptavidin is formed by the covalent coupling of Horseradish Peroxidase (HRP) with Streptavidin; it combines the highly efficient catalytic activity of the enzyme with the high affinity of Streptavidin for biotin, making it a potent and sensitive tool for signal amplification. HRP-Streptavidin is suitable for use in Western Blotting, ELISA, and other detection techniques .

HRP-Streptavidin

1 Publications Verification

Fluorescent Dyes

Sulfonylurea Receptor HRP-Streptavidin is a biotin-binding signal amplifier designed to bind tightly with biotinylated anti-TSH monoclonal antibodies, thereby constituting a key component of the signal amplification system in immunoassays. HRP-Streptavidin is formed by the covalent coupling of Horseradish Peroxidase (HRP) with Streptavidin; it combines the highly efficient catalytic activity of the enzyme with the high affinity of Streptavidin for biotin, making it a potent and sensitive tool for signal amplification. HRP-Streptavidin is suitable for use in Western Blotting, ELISA, and other detection techniques .

Cat. No.	Product Name	Target	Research Area	Image

HY-P991202

Anti-TSHR Antibody (M22)	TSH Receptor PKA	Metabolic Disease Inflammation/Immunology
Anti-TSHR Antibody (M22) is a selective agonist targeting TSHR (thyroid-stimulating hormone receptor), acting through competitive binding to the extracellular domain of TSHR. Anti-TSHR Antibody (M22) can mimic the biological effects of thyroid-stimulating hormone (TSH), activating downstream cAMP-PKA and other signaling pathways. Anti-TSHR Antibody (M22) can stimulate the proliferation of thyroid follicular epithelial cells and human umbilical vein endothelial cells (HUVECs), promote angiogenesis and tube formation, cell migration, and also upregulate the expression of angiogenesis-related proteins such as PROX1. Anti-TSHR Antibody (M22) can be used in research areas such as the mechanisms of goiter formation in Graves' disease (GD), angiogenesis regulation, and TSHR antagonist screening .

Host:	Mouse (2)
Reactivity:	Human (2)
Application:	IHC-P (2) IF-Tissue (2) IHC-F (2) ELISA (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1)
Modification:	Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86714

	CGA/hCG alpha Antibody (YA6406) GLHA_human; Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; HCG; LHA; FSHA; GPA1; GPHa; TSHA; GPHA1; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha(CG-alpha); Follicle-stimulating hormone alpha chain(FSH-alpha); Follitropin alpha chain; Luteinizing hormone alpha chain(LSH-alpha); Lutropin alpha chain; thyroid-stimulating hormone alpha chain(TSH-alpha); Thyrotropin alpha chain; glycoprotein hormones, alpha polypeptide; HCG alpha;	IHC-P, IHC-F, IF-Tissue, ELISA	Human
	CGA/hCG alpha Antibody (YA6406) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to CGA/hCG alpha.

HY-P86714A

	CGA/hCG alpha Antibody (YA6406)(PBS only) GLHA_human; Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; HCG; LHA; FSHA; GPA1; GPHa; TSHA; GPHA1; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha(CG-alpha); Follicle-stimulating hormone alpha chain(FSH-alpha); Follitropin alpha chain; Luteinizing hormone alpha chain(LSH-alpha); Lutropin alpha chain; thyroid-stimulating hormone alpha chain(TSH-alpha); Thyrotropin alpha chain; glycoprotein hormones, alpha polypeptide; HCG alpha;	IHC-P, IHC-F, IF-Tissue, ELISA	Human
	CGA/hCG alpha Antibody (YA6406) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to CGA/hCG alpha.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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