5 Results for "

iduronidase

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "iduronidase" in MCE Product Catalog:

Cat. No.: HY-W654272
CAS No.: 2181774-46-7
Synonyms: 4-MU-α-idoa 2-sulfate sodium
Target:  

Fluorescent Dye

Research Areas:  

Metabolic Disease

4-Methylumbelliferyl-α-L-iduronide 2-sulfate (4-MU-α-idoa 2-sulfate) sodium is a fluorogenic substrate of iduronate-2-sulfatase (I2S). 4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium can be hydrolyzed by lysosomal enzyme α-l-iduronidase (IDUA) and release the fluorophore 4-Methylumbelliferone (HY-N0187). 4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium can be used to detect Hurler syndrome .
loading...
    loading...
Cat. No.: HY-P99530
CAS No.: 1815583-32-4
Synonyms: AGT-181; HIRMAb-IDUA

Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Valanafusp alfa (AGT-181) is a chimeric monoclonal antibody that fuses human α-L-iduronidase (IDUA) and targets the human insulin receptor (HIR). Valanafusp alfa has brain penetrating properties, making it useful for research on mucopolysaccharidosis type I (MPS I) .
loading...
    loading...
Cat. No.: HY-P99694
CAS No.: 2396411-71-3
Synonyms: JR-171

Target:  

Transferrin Receptor

Research Areas:  

Neurological Disease

Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I .
loading...
    loading...
Cat. No.: HY-E70622
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

α-L-Iduronidase is key in the catabolism of glycosaminoglycans (GAG) heparan and dermatan sulfate. Measurement of α-L-iduronidase specific enzyme activity is an essential parameter for those studying mucopolysaccharidoses (MPS) type I .
loading...
    loading...
Cat. No.: HY-P72242
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IDUA; iduronidase, Alpha-L-; Alpha-L-iduronidase; iduronidase Alpha-L-; MPS1; IDUA Protein; MPSI; IDA; Mucopolysaccharidosis Type I
Species:  
Source:  
loading...
    loading...