13 Results for "

igfbp+7

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "igfbp+7" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
2
Gypenoside XLIX
Gypenoside XLIX
0 Images
2 Cited Publications
製品番号: HY-N1990
CAS 番号: 94987-08-3
Category:  

Cardiovascular Disease Triterpenes Terpenoids Cucurbitaceae Plants Disease Research Fields Gynostemma pentaphyllum (Thunb.) Makino

Target:  

PPAR Sirtuin Keap1-Nrf2 Toll-like Receptor (TLR) NF-κB Reactive Oxygen Species (ROS) NOD-like Receptor (NLR) Apoptosis Pyroptosis Autophagy

Gypenoside XLIX is a multifunctional bioactive compound that can be isolated from Gynostemma pentaphyllum, with a Ka value of 1.58 μM for its binding to SIRT1. Gypenoside XLIX acts as a PPAR-α agonist. It inhibits the activation of TLR4-mediated NF-κB signaling pathway by activating the Sirt1/Nrf2 signaling pathway, reduces ROS accumulation, and alleviates hepatic inflammatory injury in mice with sepsis-induced liver disease. Gypenoside XLIX targets SIRT1 to block YAP-NLRP3 activation and improve sepsis-induced cardiomyopathy. Gypenoside XLIX inhibits apoptosis (Apoptosis), pyroptosis (Pyroptosis), autophagy (Autophagy), lipid peroxidation, pro-inflammatory cytokines and anti-inflammatory cytokines. Gypenoside XLIX alleviates sepsis-induced splenic injury by inhibiting inflammation and oxidative stress, and mitigates sepsis-associated encephalopathy by targeting PPAR-α. Gypenoside XLIX prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death and inflammation. Gypenoside XLIX inhibits the expression and activity of vascular cell adhesion molecule-1 in cytokine-induced human endothelial cells. Gypenoside XLIX is applicable to research related to acute liver injury, lung injury, cardiomyopathy, acute splenic injury, sepsis-associated encephalopathy, acute kidney injury, atherosclerosis and chronic inflammation [7].
1
IGFBP-7 Protein, Human (HEK293, His)
IGFBP-7 Protein, Human (HEK293, His)
0 Images
1 Cited Publications
製品番号: HY-P70726
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Insulin-like growth factor-binding protein 7; IGFBP7; IGF-binding protein 7; IGFBP-rP1; MAC25 protein; Tumor-derived adhesion factor; TAF
Species:  
Human
Source:  
HEK293
IGFBP7 Human Pre-designed siRNA Set A
IGFBP7 Human Pre-designed siRNA Set A
製品番号: HY-RS06630
Target:  

Small Interfering RNA (siRNA)

研究分野:  

Others

IGFBP7 Human Pre-designed siRNA Set A contains three designed siRNAs for IGFBP7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Igfbp7 Mouse Pre-designed siRNA Set A
Igfbp7 Mouse Pre-designed siRNA Set A
製品番号: HY-RS17134
Target:  

Small Interfering RNA (siRNA)

研究分野:  

Others

Igfbp7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Igfbp7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Igfbp7 Rat Pre-designed siRNA Set A
Igfbp7 Rat Pre-designed siRNA Set A
製品番号: HY-RS23580
Target:  

Small Interfering RNA (siRNA)

研究分野:  

Others

Igfbp7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Igfbp7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

IGFBP-7 Protein, Mouse (HEK293, Fc)
IGFBP-7 Protein, Mouse (HEK293, Fc)
0 Images
製品番号: HY-P74844
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: IBP-7; IGFBP7; IGFBP-7v; Insulin-like growth factor binding protein 7
Species:  
Mouse
Source:  
HEK293
IGFBP-7 Protein, Human (HEK293, K95R, His)
IGFBP-7 Protein, Human (HEK293, K95R, His)
0 Images
製品番号: HY-P703905
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Insulin-like growth factor-binding protein 7; IGFBP7; TAF; MAC25; PSF
Species:  
Human
Source:  
HEK293
IGFBP-7 Protein, Human (Biotinylated, HEK293, hFc, Avi)
IGFBP-7 Protein, Human (Biotinylated, HEK293, hFc, Avi)
0 Images
製品番号: HY-P703906
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: Insulin-like growth factor-binding protein 7; IGFBP7; TAF; MAC25; PSF
Species:  
Human
Source:  
HEK293
IGFBP-7 Protein, Human (Biotinylated, HEK293, His-Avi)
IGFBP-7 Protein, Human (Biotinylated, HEK293, His-Avi)
0 Images
製品番号: HY-P705032
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Insulin-like growth factor-binding protein 7; IGFBP7; TAF; MAC25; PSF
Species:  
Human
Source:  
HEK293
IGFBP-7 Protein, Human (HEK293, Fc)
IGFBP-7 Protein, Human (HEK293, Fc)
0 Images
製品番号: HY-P73142
純度:  ≥ 95%, as determined by Bis-Tris PAGE.
別名: Insulin-like growth factor-binding protein 7; IGFBP7; TAF; MAC25; PSF
Species:  
Human
Source:  
HEK293
IGFBP-7 Protein, Mouse (HEK293, His)
IGFBP-7 Protein, Mouse (HEK293, His)
0 Images
製品番号: HY-P70858
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Insulin-like growth factor-binding protein 7; IGFBP7; IGF-binding protein 7; IGFBP-rP1; MAC25 protein; Tumor-derived adhesion factor; TAF
Species:  
Mouse
Source:  
HEK293
IGFBP7 Antibody (YA3079)
IGFBP7 Antibody (YA3079)
0 Images
製品番号: HY-P83334
別名: IGFBP7; MAC25; PSF; Insulin-like growth factor-binding protein 7; IBP-7; IGF-binding protein 7; IGFBP-7; IGFBP-rP1; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; Tumor-derived adhesion factor; TAF

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

IGFBP7 Antibody (YA3079)(PBS only)
IGFBP7 Antibody (YA3079)(PBS only)
0 Images
製品番号: HY-P83334A
別名: IGFBP7; MAC25; PSF; Insulin-like growth factor-binding protein 7; IBP-7; IGF-binding protein 7; IGFBP-7; IGFBP-rP1; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; Tumor-derived adhesion factor; TAF

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

  • 1
Assay Types