3 Results for "

immunosuppression agent

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "immunosuppression agent" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99044
CAS No.: 2252262-24-9
Synonyms: MBG453

Target:  

Tim3

Research Areas:  

Inflammation/Immunology Cancer

Sabatolimab (MBG453) is a high-affinity, humanized, IgG4 (S228P) antibody targeting TIM-3, an inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab is a potential immunosuppression agent that can target TIM-3 on immune and myeloid cells .
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Cat. No.: HY-P99641
CAS No.: 1808081-43-7

Research Areas:  

Cancer

Gilvetmab is a canine-derived anti-cPD-1 monoclonal antibody, as well as an immune activator/antitumor agent. Gilvetmab binds to canine PD-1, blocks the interaction of PD-1/PD-L1/L2, prevents immunosuppression, reactivates antitumor responses, induces tumor regression or disease stabilization, and may also trigger pseudoprogression. Gilvetmab can be used in research related to malignant melanoma and mast cell tumors .
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Cat. No.: HY-13766
CAS No.: 179033-51-3
Synonyms: VX-853
Target:  

PPAR

Research Areas:  

Others

Timcodar is a macrolide agent, and studies have shown that during adipogenesis, timcodar can significantly inhibit fat accumulation, with an effect similar to that of rapamycin. However, unlike rapamycin, timcodar does not cause immunosuppression and glucose resistance. In addition, timcodar can effectively inhibit the adipogenic transcriptional regulators PPAR?? and C/EBP??, thereby inhibiting genes involved in fat accumulation. These studies lay the foundation for timcodar as a potential anti-obesity therapy, as obesity is becoming a global epidemic.
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