5 Results for "

mSGLT2

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "mSGLT2" in MCE Product Catalog:

  • Isoforms Recommended:
47
47 Publications Verification
Cat. No.: HY-10451
CAS No.: 842133-18-0
Purity:  99.70%
Synonyms: JNJ 28431754
Target:  

SGLT

Research Areas:  

Metabolic Disease Cancer

Canagliflozin (JNJ 28431754) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively .
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47
47 Publications Verification
Cat. No.: HY-I0383
CAS No.: 928672-86-0
Synonyms: JNJ 28431754 hemihydrate
Target:  

SGLT

Research Areas:  

Metabolic Disease Cancer

Canagliflozin hemihydrate (JNJ28431754 hemihydrate) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively .
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17
17 Cited Publications
Cat. No.: HY-N0143A
CAS No.: 7061-54-3
Synonyms: Floridzin dihydrate
Phlorizin (Floridzin) dihydrate is an orally active non-selective sodium-glucose cotransporter (SGLT) inhibitor, with an IC50 of 0.04 μM and a Ki of 39 nM against hSGLT2, and an IC50 of 0.17 μM and a Ki of 0.31 μM against hSGLT1. Phlorizin dihydrate promotes GLUT4 translocation, inhibits gluconeogenesis and promotes glycogen synthesis by activating the PI3K/Akt/mTOR pathway. Phlorizin dihydrate reduces DNA damage and apoptosis (apoptosis) by inhibiting the NF-κB inflammatory pathway. Phlorizin dihydrate induces apoptosis via activating the Caspase pathway by antagonizing the JAK/STAT3 and PCK pathways. Phlorizin dihydrate also exhibits antibacterial, anti-inflammatory and neuroprotective activities [2] .
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Cat. No.: HY-10451R
CAS No.: 842133-18-0
Synonyms: JNJ 28431754 (Standard)
Research Areas:  

Metabolic Disease Cancer

Canagliflozin (Standard) is the analytical standard of Canagliflozin. This product is intended for research and analytical applications. Canagliflozin (JNJ 28431754) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively .
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Cat. No.: HY-10451S2
Synonyms: JNJ 28431754-d6
Canagliflozin-d6 is the deuterium labeled Canagliflozin . Canagliflozin (JNJ 28431754) is a selective SGLT2 inhibitor with IC50s of 2 nM, 3.7 nM, and 4.4 nM for mSGLT2, rSGLT2, and hSGLT2 in CHOK cells, respectively [2].
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