3 Results for "

middle-aged rats

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "middle-aged rats" in MCE Product Catalog:

3,5,7,3′,4′-Pentamethoxyflavone
3,5,7,3′,4′-Pentamethoxyflavone
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Cat. No.: HY-N7690
CAS No.: 1247-97-8
Category:  

Flavonoids Flavones Metabolic Disease Plants Disease Research Fields Zingiberaceae

Target:  

Calcium Channel

3,5,7,3’,4’-Pentamethoxyflavone is a Ca 2+ channel inhibitor. 3,5,7,3’,4’-Pentamethoxyflavone can protect DNA from oxidative damage. 3,5,7,3’,4’-Pentamethoxyflavone can induce relaxation of the human corpus cavernosum through calcium mobilization-related mechanisms. 3,5,7,3’,4’-Pentamethoxyflavone can promote the expression of eNOS and cystathionine gamma lyase CSE proteins in middle-aged male rats and regulate vascular function. 3,5,7,3’,4’-Pentamethoxyflavone can be used in research related to diabetes and cardiovascular diseases .
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Pegevongitide
Pegevongitide
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Cat. No.: HY-P10887
CAS No.: 2988012-71-9
Synonyms: AV-001
Target:  

Tie ANGPTL SARS-CoV Aquaporin TNF Receptor PAI-1 CXCR P-selectin

Research Areas:  

Cardiovascular Disease Infection Neurological Disease

Pegevongitide (AV-001) is a Tie2 agonist. Pegevongitide resists the increased endothelial cell permeability induced by SARS-CoV-2 infection. Pegevongitide activates the angiogenin (angiogenin)/Tie2 signaling pathway. Pegevongitide reduces perivascular space dilation and upregulates perivascular Aquaporin-4 expression. Pegevongitide decreases the expression of TNF-α, PAI-1, CXCL9 and P-selectin, improves white matter integrity, enhances cognitive function and exerts neuroprotective effects. Pegevongitide improves white matter integrity in middle-aged rats with vascular dementia induced by multiple microinfarctions . Pegevongitide can be used in related research on diseases such as COVID-19 and vascular dementia .
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3,5,7,3′,4′-Pentamethoxyflavone (Standard)
3,5,7,3′,4′-Pentamethoxyflavone (Standard)
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Cat. No.: HY-N7690R
CAS No.: 1247-97-8
Category:  

Flavonoids Flavones Plants Zingiberaceae

Target:  

Reference Standards Calcium Channel

3,5,7,3’,4’-Pentamethoxyflavone is a Ca2+ channel inhibitor. 3,5,7,3’,4’-Pentamethoxyflavone can protect DNA from oxidative damage. 3,5,7,3’,4’-Pentamethoxyflavone can induce relaxation of the human corpus cavernosum through calcium mobilization-related mechanisms. 3,5,7,3’,4’-Pentamethoxyflavone can promote the expression of eNOS and cystathionine gamma lyase CSE proteins in middle-aged male rats and regulate vascular function. 3,5,7,3’,4’-Pentamethoxyflavone can be used in research related to diabetes and cardiovascular diseases .
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