56 Results for "

mpeg2000

" in MedChemExpress (MCE) Product Catalog:
Products (56)

56 Results for "mpeg2000" in MCE Product Catalog:

24
24 Publications Verification
Art. -Nr.: HY-112764
CAS. Nr.: 160743-62-4
Reinheit:  98.40%
DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
1
1 Cited Publications
Art. -Nr.: HY-142978
CAS. Nr.: 156543-00-9
Synonyms: DSPE-mpeg2000
18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a kind of amphiphilic polymer material. 18:0 mPEG2000 PE ammonium combines hydrophobic lipids (18:0 stearic acid chain) with hydrophilic polyethylene glycol (2 kDa) chains to form amphiphilic molecules, which are used to construct stable liposomes/nanoparticles, thereby enhancing drug delivery, prolonging circulation time, and achieving targeted effects through its functional terminal groups (usually biotin or carboxyl groups). 18:0 mPEG2000 PE ammonium can be used for the research of nanoprobes and drug delivery .
1
1 Cited Publications
Art. -Nr.: HY-112760
CAS. Nr.: 247925-28-6
Reinheit:  ≥98.0%
Synonyms: DSPE-mpeg2000 sodium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] sodium
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .
1
1 Cited Publications
Art. -Nr.: HY-144013
CAS. Nr.: 474922-77-5
Synonyms: DSPE-mpeg2000 ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:0 mPEG2000 PE ammonium can be used for drug delivery .
Art. -Nr.: HY-140676
CAS. Nr.: 80506-64-5
Reinheit:  99.57%
Synonyms: mpeg2000-NH2
mPEG2000-amine (mPEG2000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG2000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
Art. -Nr.: HY-140706
CAS. Nr.: 134874-49-0
Reinheit:  ≥98.0%
Synonyms: mpeg2000-SH
Target:  

PROTAC Linkers

Forschungsgebiete:  

Cancer

m-PEG2000-thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Art. -Nr.: HY-W591424
CAS. Nr.: 92451-01-9
Synonyms: mpeg2000-SC; mpeg2000-Succinimidyl ester
m-PEG2000-NHS ester (mPEG2000-SC) is a reagent with both cell adhesion inhibition and peptide conjugation functions. The NHS ester group of m-PEG2000-NHS ester forms stable amide bonds with primary amine-containing molecules (e.g., the N-terminus of MMP-2-cleavable octapeptide) to generate mPEG-peptide intermediates for liposome surface modification. When m-PEG2000-NHS ester is immobilized on a cystamine-modified gold surface, it can construct an in vitro model for cell adhesion kinetic studies, and higher PEG density and thicker layers correlate with lower cell adhesion rates. m-PEG2000-NHS ester can synthesize MMP-2-responsive PEGylated lipid conjugates to achieve MMP-triggered dePEGylation in the tumor microenvironment. m-PEG2000-NHS ester can be used in studies related to colon cancer and other conditions .
Art. -Nr.: HY-W1048558A
Synonyms: mpeg2000-COOH
mPEG2000-CM (mPEG2000-COOH) is a carboxyl-terminated monomethoxy polyethylene glycol. mPEG2000-CM bears a reactive carboxyl group (-COOH) at its structural terminal site, which can form stable amide bonds with amino groups and ester bonds with hydroxyl groups. mPEG2000-CM binds to PCA-g-PCL copolymers via electrostatic interaction to form polyion complex micelles with a hydrophilic PEG surface, which enhances the stability of micelles in aqueous media. mPEG2000-CM can be used for drug delivery .
Art. -Nr.: HY-140696
CAS. Nr.: 9004-74-4
Reinheit:  ≥97.0%
Synonyms: mpeg2000-Hydroxy; Polyethylene glycol monomethyl ether 2000
Forschungsgebiete:  

Cancer

m-PEG2000-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
Art. -Nr.: HY-W440988
DOPE-mPEG2000 is a phospholipid polydisperse PEG (or DOPE liposome), can be used for preparation of targeted delivery of liposomal drug and giant unilamellar vesicles (GUVs). DOPE-mPEG2000 significantly reduces the pH-sensitivity of the liposome in a concentration dependent manner .
Art. -Nr.: HY-D2840D
FITC-mPEG2000 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG2000 can be used for fluorescent labeling and imaging .
Art. -Nr.: HY-W1049092
mPEG2000-N3 can be used to modify proteins, peptides, and other materials. The azide group can react with alkynes in aqueous solution catalyzed by copper. It can also be easily reduced to an amine group. PEGylation can increase solubility and stability and reduce the immunogenicity of peptides and proteins. mPEG2000-N3 can also inhibit the nonspecific binding of charged molecules to the modified surface .
Art. -Nr.: HY-174962A
mPEG2000-Biotin is a biotin-conjugated PEG derivative used for biotinylation of biomolecules or other surfaces. Biotin can be detected by biotin/streptavidin binding assays and is widely used for molecular target detection .
Art. -Nr.: HY-P10392AF
Target:  

Wnt β-catenin

Forschungsgebiete:  

Cancer

fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits Wnt/β-catenin signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .
Art. -Nr.: HY-166979
Stearic acid-mPEG2000 is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. Stearic acid-mPEG2000 can be used in drug delivery research .
Art. -Nr.: HY-P10277
CAS. Nr.: 2222514-07-8
Synonyms: Transcon PTH; ACP-014
Target:  

Peptides

Forschungsgebiete:  

Endocrinology

Palopegteriparatide (Transcon PTH) is a prodrug of parathyroid hormone PTH 1-34, which can maintain normal and stable calcium concentrations without the need for calcium and active vitamin D replacement. Palopegteriparatide can be used in research on hypoparathyroidism .
Art. -Nr.: HY-165156
CAS. Nr.: 459429-07-3
Synonyms: 1,2-DPPE-mpeg(2000)
Target:  

Liposome

Forschungsgebiete:  

Others

DPPE-MPEG 2000 (1,2-DPPE-MPEG(2000)) is a PEG-modified lipids. DPPE-MPEG 2000 can reduce the nonspecific adsorption of protein and prolong circulation time in vivo .
Art. -Nr.: HY-P10896
CAS. Nr.: 1446005-10-2
Target:  

Bombesin Receptor

Forschungsgebiete:  

Cancer

NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT .
Art. -Nr.: HY-W1123932A
Synonyms: mpeg2000-Folate
mPEG2000-FA (mPEG2000-Folate) is a polyethylene glycol derivative of Folic acid (HY-16637). Folic acid has a high affinity for folate receptors and can be used for cell membrane receptors for targeted drug delivery .
Art. -Nr.: HY-174955A
mPEG2000-Silane is a PEG derivative containing silane that can be used to modify glass, silicon or other surfaces by reacting the hydroxyl groups with ethoxy (methoxy) silane .