80506-64-5
80506-64-5
Chemical Structure
mPEG2000-amine
Synonym(s): mPEG2000-NH2
- CAS No.: 80506-64-5
- Formula:(C2H4O)nC3H9NO
- Molecular Weight:2000 (Average)
SMILES: COCCOCCN.[n]
Biological Activity: mPEG2000-amine (mPEG2000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG2000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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mPEG2000-amine | 99.57% | mPEG2000-amine (mPEG2000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG2000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems. | ||||||||||||||||||||
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mPEG750-amine | 90.0% | mPEG750-amine (mPEG750-NH2) is a chemical modification reagent for nanoparticles, capable of covalently binding to Ad-PVA to form Ad-PVA-PEG polymers. mPEG750-amine stabilizes gene delivery complexes by providing steric hindrance, reducing particle aggregation, while enhancing the water solubility and serum stability of the complex, reducing carrier cytotoxicity, and assisting in the efficient condensation of pDNA by cationic components to form nanoparticles that can be endocytosed by cells. mPEG750-amine can also be used to synthesize folate-conjugated polymer micelles for encapsulating the anticancer agent Camptothecin (HY-16560). Folate-conjugated polymer micelles are effective carriers for poorly soluble anticancer drugs, capable of avoiding macrophages and acting through folate receptor (FR)-mediated endocytosis to target tumor cells. mPEG750-amine can be applied to research in the field of non-viral gene delivery, as a component of gene delivery vectors, facilitating the safe and efficient delivery of nucleic acid drugs to target cells. | ||||||||||||||||||||
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mPEG4000-amine | mPEG4000-amine can be used to synthesize folate-conjugated polymer micelles for encapsulating anticancer agent 9-nitrocamptothecin (HY-16560). folate-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR). | |||||||||||||||||||||
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mPEG350-amine | mPEG350-amine (mPEG350-NH2) is a PEG-based amine that serves as a precursor for the synthesis of PEG acrylamide macromonomers. mPEG350-amine is used for the synthesis of polymeric micelles for drug delivery. | |||||||||||||||||||||
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mPEG5000-amine | 99.79% | mPEG5000-amine (mPEG5000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG5000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems. | ||||||||||||||||||||
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mPEG20000-amine | 98.0% | mPEG20000-amine (mPEG20000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG20000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems. | ||||||||||||||||||||
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mPEG3400-amine | mPEG3400-amine (mPEG3400-NH2) is a PEG-based amine. It can be used to synthesize polymer micelles for drug delivery. | |||||||||||||||||||||
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mPEG1000-amine | 99.19% | mPEG1000-amine (mPEG1000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG1000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems. | ||||||||||||||||||||
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mPEG10000-amine | 99.87% | mPEG10000-amine (mPEG10000-NH2) is a monofunctional polyethylene glycol derivative-a linear PEG capped with a methoxy group at one end and a primary amino group at the other-commonly used as a hydrophilic linker in bioconjugation. | ||||||||||||||||||||
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mPEG550-amine | 98.0% | mPEG550-amine (mPEG550-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG550-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems. | ||||||||||||||||||||
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