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  3. mPEG1000-amine

mPEG1000-amine  (Synonyms: mPEG1000-NH2)

Cat. No.: HY-140675 Purity: 99.19%
Handling Instructions Technical Support

mPEG1000-amine (mPEG1000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG1000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.

For research use only. We do not sell to patients.

mPEG1000-amine

mPEG1000-amine Chemical Structure

CAS No. : 80506-64-5

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Description

mPEG1000-amine (mPEG1000-NH2) is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. mPEG1000-amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.

IC50 & Target

PEGs

 

In Vitro

mPEG-amines of different molecular weights are suitable for different research scenarios. For example, low molecular weight (e.g., MW 350-2000 Da) is often used for small molecule coupling or surface modification, while high molecular weight (e.g., MW 5000-20000 Da) is more suitable for prolonging in vivo circulation time or constructing steric hindrance layers.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1000 (Average)

Formula

(C2H4O)nC3H9NO

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

COCCOCCN.[n]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 200 mg/mL (Need ultrasonic)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.19%

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
mPEG1000-amine
Cat. No.:
HY-140675
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