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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
murine osteoblasts
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "murine osteoblasts" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P5522A
Synonyms: L-Ala-γ-D-Glu-meso-diaminopimelic acid dihydrochloride
Research Areas:
Cat. No.: HY-P5522
CAS No.: 877462-71-0
Synonyms: L-Ala-γ-D-Glu-meso-diaminopimelic acid
Research Areas:
Cat. No.: HY-W250160
CAS No.: 100403-24-5
Synonyms: Polydeoxyribonucleotide
Category:
Cat. No.: HY-13752
CAS No.: 1118915-78-8
STA-1474 is an orally active and highly selective HSP90 inhibitor, as well as a phosphate prodrug of the HSP90 inhibitor STA-9090 (HY-15205). STA-1474 disrupts the chaperone function of HSP90 and promotes the degradation of client proteins. STA-1474 inhibits the phosphorylation of Met, Akt and STAT3, thereby blocking related signaling pathways. STA-1474 induces apoptosis and inhibits proliferation of osteosarcoma cells, and triggers the up-regulation of HSP70 and HSP90. STA-1474 induces tumor regression and caspase-3 activation in mouse osteosarcoma xenograft models. STA-1474 can be used in the research of osteosarcoma .
Cat. No.: HY-206972
CAS No.: 26063-00-3
Target:
Research Areas:
Poly (3-hydroxybutyrate) is a bacterially derived (R)-3-hydroxybutyrate homopolymer and a degradable biomaterial. Poly (3-hydroxybutyrate) degrades in vivo via lipases and esterases, breaking down into 3-Hydroxybutyric acid (HY-113378). Poly (3-hydroxybutyrate) can be compounded with 15% Hydroxyapatite (HA) (HY-D0835A) or 7.5-10% nanobioglass for use as a bone scaffold .
Cat. No.: HY-13752B
CAS No.: 1402907-09-8
STA-1474 sodium is an orally active and highly selective HSP90 inhibitor, as well as a phosphate prodrug of the HSP90 inhibitor STA-9090 (HY-15205). STA-1474 sodium disrupts the chaperone function of HSP90 and promotes the degradation of client proteins. STA-1474 sodium inhibits the phosphorylation of Met, Akt and STAT3, thereby blocking related signaling pathways. STA-1474 sodium induces apoptosis and inhibits proliferation of osteosarcoma cells, and triggers the up-regulation of HSP70 and HSP90. STA-1474 sodium induces tumor regression and caspase-3 activation in mouse osteosarcoma xenograft models. STA-1474 sodium can be used in the research of osteosarcoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
