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Results for "

non-native state

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-NP008
    β-Lactoglobulin

    		Lipocalin Family Inflammation/Immunology
    β-Lactoglobulin, a major whey protein, is a small globular protein from the lipocalin family. β-Lactoglobulin is an important source of the essential and branched-chain amino acids (leucine, isoleucine, and valine). β-Lactoglobulin shows antioxidant properties, because it contains two disulfide bonds and one free thiol group. β-Lactoglobulin is a ligand transport agent. β-Lactoglobulin is one of the major allergens in milk and can be utilized in the research for developing safe hypoallergenic dairy products .
    β-Lactoglobulin
  • HY-181085
    RD0448

    		DYRK Neurological Disease Inflammation/Immunology Cancer
    RD0448 is a potent inhibitor of DYRK1A, DYRK1B, and DYRK2. RD0448 selectively targets the non-native (folded intermediate) state of DYRK1A and DYRK1B. The binding site of RD0448 is hidden in the native state of DYRK1A and DYRK1B, and as a stabilizing binder, it binds tightly to both DYRK1A and DYRK1B, forming a stable complex with slow dissociation kinetics. In contrast, RD0448 targets the native state of DYRK2 without selectivity between its native and non-native states, acting as a weak binder with weaker binding affinity to DYRK2 and forming a rapidly dissociating complex .
    RD0448

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