4 Results for "

osteomalacia

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "osteomalacia" in MCE Product Catalog:

6
Secalciferol
Secalciferol
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6 Cited Publications
Cat. No.: HY-32343
CAS No.: 55721-11-4
Synonyms: (24R)-24,25-Dihydroxyvitamin D3
Category:  

Endogenous metabolite Disease Research Fields Inflammation/Immunology Steroids

Target:  

Endogenous Metabolite VD/VDR

Secalciferol ((24R)-24,25-Dihydroxyvitamin D3) is the major active metabolite of Vitamin D. Secalciferol activates vitamin D receptor (VDR) with an EC50 value of 150 nM. Secalciferol is involved in a wide range of biological functions such as calcium homeostasis, cellular differentiation and proliferation processes, as well as other functions related to the immune system, which is promising for research of rickets, osteomalacia, hypercalcemia and autoimmune disorders .
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1
Burosumab
Burosumab
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1 Cited Publications
Cat. No.: HY-P9939
CAS No.: 1610833-03-8
Synonyms: KRN23; N5KG1_C10_LH; UX-023

Target:  

Inhibitory Antibodies

Research Areas:  

Metabolic Disease Cancer

Burosumab (KRN23) is a humanized FGF23-neutralizing antibody. By neutralizing FGF23, Burosumab blocks its inhibitory effect on renal phosphate reabsorption, thereby increasing serum phosphate levels and improving abnormal bone mineralization. Burosumab can be used in the research of diseases such as X-linked hypophosphatemia (XLH) and osteomalacia .
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Calcium gluconate
Calcium gluconate
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Cat. No.: HY-W145486
CAS No.: 299-28-5
Calcium gluconate is an orally effective calcium salt supplement . Calcium gluconate reduces elevated serum potassium, decreased serum calcium, and postoperative myalgia associated with succinylcholine administration. Calcium gluconate restores calcium homeostasis, skeletal integrity, bone mineralization and bone density, and maintains levels of parathyroid hormone, bone resorption markers and osteoclasts. Calcium gluconate reverses LPS (HY-D1056)-induced ERK phosphorylation, inflammatory cytokine release and acute lung injury, alleviates airway inflammatory damage and suppresses immune responses. Calcium gluconate can be used in research related to postoperative myalgia, osteoporosis/osteomalacia and acute lung injury .
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25,26-Dihydroxyvitamin D3
25,26-Dihydroxyvitamin D3
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Cat. No.: HY-15830
CAS No.: 29261-12-9
Purity:  95.47%
Synonyms: 25,26-Dihydroxycholecalciferol
Category:  

Natural Products Other Diseases Endogenous metabolite Disease Research Fields

Target:  

VD/VDR Drug Metabolite Drug Derivative Calcium Channel

25,26-Dihydroxyvitamin D3 (25,26-Dihydroxycholecalciferol) is a dihydroxylated derivative and metabolite of Vitamin D3 (HY-15398). 25,26-Dihydroxyvitamin D3 moderately increases serum calcium levels when the initial serum calcium level is low. 25,26-Dihydroxyvitamin D3 promotes intestinal calcium absorption in vitamin D-deficient rats fed a low-calcium diet. 25,26-Dihydroxyvitamin D3 is applicable to research related to osteomalacia .
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