4 Results for "

peptide-based linker

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "peptide-based linker" in MCE Product Catalog:

Cat. No.: HY-P3371
CAS No.: 2484870-92-8
Synonyms: DS-7300a; MABX-9001a; I-DXd
Ifinatamab deruxtecan (DS-7300a) is a B7-H3-targeting Antibody-drug conjugate (ADC), which is composed of a humanized anti-B7-H3 monoclonal antibody, an enzymatically cleavable peptide-based linker, and Exatecan derivative (DXd) (HY-13631D). Ifinatamab deruxtecan is a DNA Topoisomerase I inhibitor. Ifinatamab deruxtecan induces Apoptosis. DS-7300a exerts potent antitumor activities against B7-H3-expressing tumors. against rhabdomyosarcoma, endometrial adenocarcinoma and lung adenocarcinoma. Ifinatamab deruxtecan does not exert direct immunomodulatory effects
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Cat. No.: HY-P11228
Research Areas:  

Cancer

FPP29 is a potent peptide-based FOXM1 PROTAC degrader. FPP29 induces ubiquitination and degradation of FOXM1. FPP29 inhibits FOXM1 via the ubiquitin-proteasome degradation pathway. FPP29 induces Apoptosis. FPP29 suppresses tumor growth in hepatocellular carcinoma xenograft models. FPP29 can be used in the research of hepatocellular carcinoma (cell-penetrating peptide: (HY-P0133); VHL ligase ligand: (HY-P11493); linker: (HY-W013664); FOXM1 ligand: (HY-P11494)) .
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Cat. No.: HY-147021
CAS No.: 1350456-66-4
Target:  

ADC Linkers

Research Areas:  

Cancer

MC-Val-D-Cit-PAB-PNP is a peptide linker that can be used for the synthesis of Antibody-Drug Conjugates (ADCs). MC-Val-D-Cit-PAB-PNP can be used to construct antibody-drug conjugates loaded with ATR/CHK1 inhibitors .
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Cat. No.: HY-147021A
CAS No.: 1350456-64-2
Target:  

ADC Linkers

Research Areas:  

Cancer

MC-D-Val-Cit-PAB-PNP is a peptide linker that can be used for the synthesis of Antibody-Drug Conjugates (ADCs). MC-D-Val-Cit-PAB-PNP can be used to construct antibody-drug conjugates loaded with ATR/CHK1 inhibitors .
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