26 Results for "

plasmid+DNA

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "plasmid+DNA" in MCE Product Catalog:

24
mPEG2000-DMG
mPEG2000-DMG
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24 Cited Publications
Cat. No.: HY-112764
CAS No.: 160743-62-4
Purity:  98.40%
DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
2
PEG8000
PEG8000
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2 Cited Publications
Cat. No.: HY-Y0873J
CAS No.: 25322-68-3
Synonyms: Polyethylene glycol 8000
Target:  

Environmental Pollutants Biochemical Assay Reagents

Research Areas:  

Others

PEG8000 can be used for phage precipitation, isolation of plasmid DNA, and promotion of flat end-junction reactions .
Polyethylenimine (branched) (MW 25000)
Polyethylenimine (branched) (MW 25000)
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Cat. No.: HY-W250110E
CAS No.: 9002-98-6
Synonyms: PEI (branched) (MW 25000)
Target:  

Environmental Pollutants DNA Alkylator/Crosslinker Biochemical Assay Reagents

Research Areas:  

Others

Polyethylenimine (branched) is a commonly used non-viral DNA transfection reagent. Polyethylenimine (branched) (MW 25000) binds to plasmid DNA .
3-Azidopropylamine
3-Azidopropylamine
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Cat. No.: HY-151862
CAS No.: 88192-19-2
Purity:  99.57%
Target:  

ADC Linkers PROTAC Linkers

Research Areas:  

Others

3-Azidopropylamine is a click chemistry reagent containing an azide group. 3-Azidopropylamine can react with the starch sugar of potato starch for complexation and transfection of plasmid DNA . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
DHICA
DHICA
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Cat. No.: HY-W018158
CAS No.: 4790-08-3
Synonyms: 5,6-Dihydroxyindole-2-carboxylic acid
Target:  

Endogenous Metabolite GPR35 Arrestin DNA/RNA Synthesis Drug Intermediate SOD

Research Areas:  

Cancer

DHICA (5,6-Dihydroxyindole-2-carboxylic acid) is an eumelanin building block, GPR35 agonist and melanin synthesis intermediate. DHICA activates GPR35, triggering dynamic mass redistribution and β-arrestin translocation. DHICA interacts with DNA and interferes with Fpg activity . DHICA promotes the generation of single-strand breaks in plasmid DNA. DHICA increases the activity and expression levels of SOD and Catalase. DHICA is applicable to research related to skin cancer and colon cancer .
LAH4
LAH4
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Cat. No.: HY-P0311
CAS No.: 184776-51-0
Target:  

Bacterial

Research Areas:  

Infection

LAH4, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 possesses high plasmid DNA delivery capacities. LAH4 has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .
Poly-L-lysine hydrobromide (MW 1000-5000)
Poly-L-lysine hydrobromide (MW 1000-5000)
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Cat. No.: HY-126437I
CAS No.: 25988-63-0
Poly-L-lysine hydrobromide (MW 1000-5000) is a homopolymer of L-lysine and a polycationic non-viral gene delivery vector. Poly-L-lysine hydrobromide (MW 1000-5000) forms complexes with plasmid DNA. Poly-L-lysine hydrobromide (MW 1000-5000) is applicable to relevant research on lung cancer .
trans-Cyclohexane-1,2-diol
trans-Cyclohexane-1,2-diol
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Cat. No.: HY-W010514
CAS No.: 1460-57-7
Category:  

Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

trans-Cyclohexane-1,2-diol (TCHD) is a transient dilator of the nuclear pore complex (NPC). By interacting with the hydrophobic core (FG nucleoporin) of the NPC, trans-Cyclohexane-1,2-diol can disrupt the NPC structure and reversibly increase the permeability of the nuclear pore, allowing macromolecules larger than 40 kDa (such as plasmid DNA) to enter the cell nucleus by passive diffusion, thereby enhancing the nuclear import efficiency of non-viral vectors. trans-Cyclohexane-1,2-diol can improve the efficiency of in vitro electrotransfection or lipid-mediated gene transfection, especially significantly increasing gene expression in differentiated airway epithelial cells .
KALA
KALA
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Cat. No.: HY-P2530
CAS No.: 187987-64-0
Target:  

Peptides

Research Areas:  

Others

KALA is an amphiphilic peptide that forms an α-helical structure at physiological pH. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors .
LAH4 TFA
LAH4 TFA
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Cat. No.: HY-P0311A
Target:  

Bacterial

Research Areas:  

Infection

LAH4 TFA, an alpha-helix of the designed amphipathic peptide antibiotic, exhibits potent antimicrobial, nucleic acid transfection and cell penetration activities. LAH4 TFA possesses high plasmid DNA delivery capacities. LAH4 TFA has a strong affinity for anionic lipids found in the outer membrane of bacterial membranes .
Stearyl-(homoarginine)8 TFA
Stearyl-(homoarginine)8 TFA
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Cat. No.: HY-P10991A
Synonyms: Stearylated octaarginine TFA
Target:  

Biochemical Assay Reagents

Research Areas:  

Others

Stearyl-(homoarginine)8 (Stearylated octaarginine) TFA is an effective gene delivery vector that can deliver plasmid DNA into cells. Stearyl-(homoarginine)8 TFA can make plasmid DNA more effectively internalized into cells and improve the nuclear delivery rate .
1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine
1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine
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Cat. No.: HY-W583869
CAS No.: 6418-95-7
Synonyms: 1-Stearoyl-2-Oleoyl-sn-glycero-3-PE; 18:0-18:1 PE; PE(18:0/18:1)
Target:  

Liposome

Research Areas:  

Metabolic Disease

1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipids that contains stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for in vitro delivery of mRNA or nuclear-targeted plasmid DNA.
DHICA (Standard)
DHICA (Standard)
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Cat. No.: HY-W018158R
CAS No.: 4790-08-3
Synonyms: 5,6-Dihydroxyindole-2-carboxylic acid (Standard)
Target:  

Reference Standards Endogenous Metabolite GPR35 Arrestin DNA/RNA Synthesis Drug Intermediate SOD

Research Areas:  

Cancer

DHICA (Standard) is an analytical standard of DHICA (HY-W018158). This product is for research and analytical applications. DHICA (5,6-Dihydroxyindole-2-carboxylic acid) is an eumelanin building block, GPR35 agonist and melanin synthesis intermediate. DHICA activates GPR35, triggering dynamic mass redistribution and β-arrestin translocation. DHICA interacts with DNA and interferes with Fpg activity . DHICA promotes the generation of single-strand breaks in plasmid DNA. DHICA increases the activity and expression levels of SOD and Catalase. DHICA is applicable to research related to skin cancer and colon cancer .
Poloxamer L61
Poloxamer L61
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Cat. No.: HY-D1005I
CAS No.: 9003-11-6
Poloxamer L61 is a non-ionic triblock copolymer surfactant. Poloxamer L61 effectively achieves intracellular molecular delivery to cancer cells during photoacoustic molecular delivery, and maintains cell viability by promoting cell membrane resealing, thus avoiding irreversible damage caused by laser-induced membrane permeabilization. Poloxamer L61 is a key component of SP1017, a compound related to gene therapy, which regulates the interaction between DNA and extracellular matrix as well as cellular uptake, and significantly enhances the distribution and bioavailability of plasmid DNA in skeletal muscle. Poloxamer L61 can be used in studies on local or systemic therapeutic protein production .
Stearyl-homoarginine8
Stearyl-homoarginine8
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Cat. No.: HY-P10991
CAS No.: 383177-47-7
Synonyms: Stearylated octaarginine
Target:  

Biochemical Assay Reagents

Research Areas:  

Others

Stearyl-(homoarginine)8 (Stearylated octaarginine) is an effective gene delivery vector that can deliver plasmid DNA into cells. Stearyl-(homoarginine)8 can make plasmid DNA more effectively internalized into cells and improve the nuclear delivery rate .
Cys(Npys)-TAT (47-57)
Cys(Npys)-TAT (47-57)
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Cat. No.: HY-P4101
Target:  

HIV

Research Areas:  

Infection

Cys(Npys)-TAT (47-57) is a peptide fragment of TAT peptide and it is able to interact with plasmid DNA electrostatically. Cys(Npys)-TAT (47-57) is corresponding to the transduction domain of TAT with an activated cysteine residue C. TAT is a small nuclear transcriptional activator protein encoded by HIV-1 .
DMG-PEG 2000 (GMP Like)
DMG-PEG 2000 (GMP Like)
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Cat. No.: HY-112764GL
CAS No.: 160743-62-4
DMG-PEG 2000 (GMP Like) is DMG-PEG 2000 (HY-112764) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles .
DORI
DORI
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Cat. No.: HY-W800776
CAS No.: 153312-59-5
Synonyms: 1,2-Dioleoyl-3-dimethyl-hydroxyethylammonium bromide
Target:  

Liposome

Research Areas:  

Others

DORI is a cationic lipid that can deliver plasmid DNA in vitro. DORI has lower cytotoxicity and high transfection efficiency .
DLRIE
DLRIE
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Cat. No.: HY-153125
CAS No.: 199171-54-5
Purity:  99.41%
Target:  

Liposome

Research Areas:  

Others

DLRIE is a cationic lipid that can be used for the synthesis of liposome GAP-DLRIE. GAP-DLRIE can be used to enhance the delivery and expression of plasmid DNA. DLRIE can be used for delivery of nucleic acids .
1-Cinnamoylpyrrolidine
1-Cinnamoylpyrrolidine
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Cat. No.: HY-N1620
CAS No.: 52438-21-8
Category:  

Cardiovascular Disease Natural Products other families Plants Disease Research Fields

Target:  

DNA/RNA Synthesis Platelet-activating Factor Receptor (PAFR)

1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA . 1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC50 of 37.3 μM .
Assay Types