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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
poly-arginine
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "poly-arginine" in MCE Product Catalog:
Cat. No.: HY-172277A
Cat. No.: HY-P10055
CAS No.: 2042750-71-8
Synonyms: PSMA-1
Cat. No.: HY-172277B
Cat. No.: HY-172277C
Cat. No.: HY-P4083A
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Cat. No.: HY-179371
CAS No.: 2606032-80-6
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LIQ1, a flavonoid derivative, is a potent Pyruvate kinase M2 (PKM2) allosteric inhibitor (IC50 = 0.39 μM; Kd = 4.5 μM) targeting Arg43 within the polyarginine pocket. LIQ1 exhibits efficacy in a mouse model of LPS (HY-D1056)-induced endotoxemia, preventing the nuclear translocation of PKM2 and inhibiting its binding to HIF-1α, thereby suppressing IL-1β transcription. LIQ1 can be used for the research of endotoxemia [1].
Cat. No.: HY-181000
CAS No.: 3074520-74-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
