1 Result for "

reverse indazole

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "reverse indazole" in MCE Product Catalog:

Cat. No.: HY-160940
CAS No.: 2810880-82-9
Target:  

MAP4K

Research Areas:  

Cancer

HPK1-IN-46 (Compound 36) is an efficient and highly selective HPK1 reverse indazole inhibitor with an IC50 value of 1.1 nM. HPK1-IN-46 exhibits high selectivity for CDK2, JAK1, and JAK2. HPK1-IN-46 inhibits SLP76 phosphorylation mediated by HPK1, reverses T-cell inhibition, and enhances anti-tumor immunity. HPK1-IN-46 can be used in immunotherapy research for tumors .
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