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HPK1-IN-46

HPK1-IN-46 (Compound 36) is an efficient and highly selective HPK1 reverse indazole inhibitor with an IC50 value of 1.1 nM. HPK1-IN-46 exhibits high selectivity for CDK2, JAK1, and JAK2. HPK1-IN-46 inhibits SLP76 phosphorylation mediated by HPK1, reverses T-cell inhibition, and enhances anti-tumor immunity. HPK1-IN-46 can be used in immunotherapy research for tumors.

For research use only. We do not sell to patients.

  • CAS No.: 2810880-82-9
  • Formula: C25H25FN6O
  • Molecular Weight:444.50
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • HPK1-IN-46 Chemical Structure
  • HPK1-IN-46 Chemical Structure
    HPK1-IN-46 Chemical Structure
CAS No.: 2810880-82-9
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  • HPK1-IN-46