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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
somnolence
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "somnolence" in MCE Product Catalog:
3
3 Cited Publications
Synonyms: JNJ-42847922
Target:
Research Areas:
Seltorexant (JNJ-42847922) is an orally active, high-affinity, and selective orexin-2 receptor (OX2R) antagonist (pKi values of 8.0 and 8.1 for human and rat OX2R). Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain .
3
3 Cited Publications
Synonyms: JNJ-42847922 hydrochloride
Target:
Research Areas:
Seltorexant hydrochloride (JNJ-42847922 hydrochloride) is an orally active, high-affinity, and selective OX2R antagonist (pKi values of 8.0 and 8.1 for human and rat OX2R). Seltorexant hydrochloride crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain .
Synonyms: GLP-1 receptor agonist 11
Target:
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
GLP-1 receptor agonist 11 is a GLP-1 receptor agonist .GLP-1 receptor agonist 11 activates the GLP-1 receptor .GLP-1 receptor agonist 11 can be used for the research of diabetes, non-alcoholic fatty liver disease, glucose intolerance, dyslipidemia, syndrome x, arteriosclerosis, hypertension, obesity, hepatic fibrosis, cirrhosis, somnolence, hyperglycemia, hyperlipidemia, atherosclerosis, hypertriglyceridemia, type 1 diabetes, type 2 diabetes, diabetic dyslipidemia .
Cat. No.: HY-109012AR
CAS No.: 1293284-49-7
Synonyms: JNJ-42847922 hydrochloride (Standard)
Research Areas:
Seltorexant hydrochloride (Standard) is the analytical standard of Seltorexant (hydrochloride) (HY-109012A). This product is intended for research and analytical applications. Seltorexant hydrochloride (JNJ-42847922 hydrochloride) is an orally active, high-affinity, and selective OX2R antagonist (pKi values of 8.0 and 8.1 for human and rat OX2R). Seltorexant hydrochloride crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain .
Cat. No.: HY-109012R
CAS No.: 1293281-49-8
Synonyms: JNJ-42847922 (Standard)
Research Areas:
Seltorexant (Standard) is the analytical standard of Seltorexant (HY-109012). This product is intended for research and analytical applications. Seltorexant (JNJ-42847922) is an orally active, high-affinity, and selective orexin-2 receptor (OX2R) antagonist (pKi values of 8.0 and 8.1 for human and rat OX2R). Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain .
Cat. No.: HY-120131
CAS No.: 13067-93-1
Target:
Research Areas:
Cyanofenphos is an orally active organophosphate insecticide and brain AChE inhibitor with neurotoxicity. Cyanofenphos induces delayed neurotoxicity such as ataxia and paralysis. Cyanofenphos also causes symptoms including somnolence, reduced feed intake and weight loss in hens. Cyanofenphos has a unique self-antagonistic effect: repeated low-dose pre-treatment not only reduces subsequent acute toxicity, but also exacerbates delayed neurotoxicity and attenuates enzyme inhibition, with the protective effect peaking at 24 h after the last pre-treatment. Cyanofenphos is commonly used in studies related to delayed neurotoxicity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
