13067-93-1
Chemical Structure
Cyanofenphos
- CAS No.: 13067-93-1
- Formula:C15H14NO2PS
- Molecular Weight:303.32
IUPAC Name: O-(4-cyanophenyl) O-ethyl phenylphosphonothioate
InChIKey: LRNJHZNPJSPMGK-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(OP(=S)(OCC)C=2C=CC=CC2)C=C1
Biological Activity: Cyanofenphos is an orally active organophosphate insecticide and brain AChE inhibitor with neurotoxicity. Cyanofenphos induces delayed neurotoxicity such as ataxia and paralysis. Cyanofenphos also causes symptoms including somnolence, reduced feed intake and weight loss in hens. Cyanofenphos has a unique self-antagonistic effect: repeated low-dose pre-treatment not only reduces subsequent acute toxicity, but also exacerbates delayed neurotoxicity and attenuates enzyme inhibition, with the protective effect peaking at 24 h after the last pre-treatment. Cyanofenphos is commonly used in studies related to delayed neurotoxicity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Cyanofenphos | Cyanofenphos is an orally active organophosphate insecticide and brain AChE inhibitor with neurotoxicity. Cyanofenphos induces delayed neurotoxicity such as ataxia and paralysis. Cyanofenphos also causes symptoms including somnolence, reduced feed intake and weight loss in hens. Cyanofenphos has a unique self-antagonistic effect: repeated low-dose pre-treatment not only reduces subsequent acute toxicity, but also exacerbates delayed neurotoxicity and attenuates enzyme inhibition, with the protective effect peaking at 24 h after the last pre-treatment. Cyanofenphos is commonly used in studies related to delayed neurotoxicity. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Konno N, et al. Protective effect of pretreatment against the acute toxicity of formulated cyanofenphos in hens. Tohoku J Exp Med. 1984;142(2):155-163. [Content Brief]
- [2]. Yamauchi T, et al. Intensifying effect of repeated pretreatment for delayed neurotoxicity from organophosphorus insecticide cyanofenphos in hens[J]. Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene), 1984, 39(3): 611-620.
Keywords
