SHP2-IN-36
SHP2-IN-36 (Compound B8) is an allosteric inhibitor of SHP2, with an IC50 value of 9.0 nM. In addition, its IC50 for p-ERK is 40 nM. SHP2-IN-36 also exhibited significant antitumor activity in the KYSE520 xenograft mouse model. SHP2-IN-36 can be used for research in the field of anti-tumor .
For research use only. We do not sell to patients.
- Formula: C28H30N8OS
- Molecular Weight:526.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 526.66
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Formula C28H30N8OS
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SMILES
N[C@H]1C2(CCN(C3=NC=C(SC4=C5OC[C@@](CCC6)([H])N6C5=NC=C4)C7=NN=CN37)CC2)CC8=C1C=CC=C8
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)