Tnfsf4 - TNF superfamily member 4 Gene

Also Known as Ox40l; Tnlg2b

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 89814

Summary

Enables tumor necrosis factor receptor superfamily binding activity. Involved in T cell proliferation; positive regulation of activated T cell proliferation; and positive regulation of interleukin-2 production. Located in cell surface. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human TNFSF4 (TNF Superfamily member 4). [provided by Alliance of Genome Resources, Apr 2022]

Tnfsf4 Products (1)

mRNA Protein Name
NM_053552.2 NP_446004.1 tumor necrosis factor ligand superfamily member 4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables tumor necrosis factor receptor superfamily binding IMP
IMP: Inferred from mutant phenotype
10772947 RGD
enables tumor necrosis factor receptor superfamily binding IPI
IPI: Inferred from physical interaction
9790919 RGD
Biological Process GO Annotation Evidence References Source
involved in T cell proliferation IMP
IMP: Inferred from mutant phenotype
10772947 RGD
involved in positive regulation of activated T cell proliferation IDA
IDA: Inferred from direct assay
9790919 RGD
involved in positive regulation of interleukin-2 production IDA
IDA: Inferred from direct assay
9790919 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
9790919 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor necrosis factor ligand superfamily member 4

  • OX40 ligand

  • tumor necrosis factor (ligand) superfamily, member 4

  • tumor necrosis factor ligand 2b

  • tumor necrosis factor superfamily member 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14828 TNFSF4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17931 Tnfsf4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24401 Tnfsf4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992122 Olevaprubart 99.43% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfsf4 NCBI NCBI:7292