NH2-C16-azide
NH2-C16-azide is a 16-azidohexadecylamine derivative and synthetic intermediate, which can serve as a PROTAC Linker. NH2-C16-azide is applicable to research related to PROTAC synthesis, such as acting as the linker for PROTAC CDK9 degrader-13 (HY-184693).
For research use only. We do not sell to patients.
- CAS No.: 2755836-98-5
- Formula: C16H34N4
- Molecular Weight:282.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
NH2-C16-azide (compound 8f) serves as a linker for PROTAC CDK9 degrader-13 (HY-184693). PROTAC CDK9 degrader-13 is a selective CDK9 PROTAC degrader. It downregulates the anti-apoptotic protein Mcl-1 and activates the Caspase-3 pathway to induce apoptosis in acute myeloid leukemia cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2755836-98-5
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Molecular Weight 282.47
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Formula C16H34N4
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SMILES
NCCCCCCCCCCCCCCCCN=[N+]=[N-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NH2-C16-azide Related Classifications
HY-184695 Related Classifications
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