DNA Polymerase lambda Antibody (YA6930)
(Synonyms: BETA N antibody)DNA Polymerase lambda Antibody (YA6930) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DNA Polymerase lambda.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Monkey
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:2000 | 1:1000 |
Product Details
DNA Polymerase lambda Antibody (YA6930) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DNA Polymerase lambda.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Monkey
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Observed Molecular WeightObserved band size: 70 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size：63 kDa
Recombinant protein within human DNA Polymerase lambda aa 1-575 / 575.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DNA Polymerase lambda is a DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Also has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity[1][2][3][4][5][6][7][8][9].
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Subcellular Localization
Nucleus,Chromosome
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Expression
Tissue_Specificity: Expressed in a number of tissues. Abundant in testis -
Isoforms & Post-Translational Modification
Q9UGP5 has two isomers: Q9UGP5-1: 63482 Da (predicted); Q9UGP5-2: 33839 Da (predicted).
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Subunit
Interacts with PCNA (PubMed:14992725)
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SwissProt ID
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Synonyms
BETA N antibody
Documentation
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