Hoxb4 - homeo box B4 Gene

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including embryonic skeletal system morphogenesis; hematopoietic stem cell differentiation; and positive regulation of stem cell differentiation. Predicted to act upstream of or within several processes, including hematopoietic or lymphoid organ development; negative regulation of transcription by RNA polymerase II; and somatic stem cell division. Predicted to be located in centrosome and nucleoplasm. Predicted to be active in nucleus. Orthologous to human HOXB4 (homeobox B4). [provided by Alliance of Genome Resources, Apr 2022]