HOXB4 - homeobox B4 Gene

Also Known as HOX2; HOX2F; HOX-2.6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 3214

About HOXB4

Cytogenetic location: 17q21.32 Genomic coordinates (GRCh38): 17:48,575,507-48,578,350 (from NCBI)

This gene has 1 transcript (splice variant), 169 orthologues and 42 paralogues. Broad expression in fat (RPKM 4.1), lung (RPKM 2.6) and 19 other tissues.

Summary

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq, Jul 2008]

HOXB4 Products (1)

mRNA Protein Name
NM_024015.5 NP_076920.1 homeobox protein Hox-B4

HOXB4 Protein Structure

Homeobox

Homeobox: Homeobox domain (163 - 219)

  • 0
  • 100
  • 200
  • 251 a.a.
Protein Preferred Names Protein Names

homeobox protein Hox-B4

  • homeo box 2F

Recombinant HOXB4 Proteins

Cat. No. Product Name Accession Purity
HY-P70308 HOXB4 Protein, Human (His) P17483 (M1-L251, L175D, E176K, E178K) ≥ 95%, as determined by reducing SDS-PAGE.

HOXB4 Antibodies

Cat. No. Product Name Application Reactivity
HY-P82942 HOXB4 Antibody (YA2687) WB, ICC/IF, IP Human, Mouse, Rat

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12303 OAC1 Activator 99.85% Unkown
HY-RS06308 HOXB4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17008 Hoxb4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23451 Hoxb4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus HOXB4 MGD MGI:96185
Rattus norvegicus HOXB4 RGD RGD:1560113
Macaca mulatta HOXB4 VGNC VGNC:104618
Bos taurus HOXB4 VGNC VGNC:29920
Canis familiaris HOXB4 VGNC VGNC:58308
Others HOXB4 NCBI