Tim3
T-Cell Immunoglobulin and Mucin Containing Protein-3; CD366
Tim3 is an immunoglobulin type protein expressed exclusively on the surface of differentiated Th1 cells. It is a co-inhibitory receptor immune checkpoint protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
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Tim3 Related Products (25)
Related Products (25)
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Antibodies (2)
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Sym023
0 ImagesCat. No.: HY-P991397Sym023 is a human monoclonal antibody (mAb) targeting TIM-3/HAVCR2/CD366. Sym023 enhances immunostimulatory and anti-tumor activities. Sym023 can be used in Non-small cell lung cancer, Solid tumors and Lymphoma research.
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HFB200901
0 ImagesCat. No.: HY-P992366HFB200901 is a galectin LGALS9 inhibitor and immunostimulant that can be used in studies related to pancreatic adenocarcinoma, pancreatic intraepithelial neoplasia, KRASG12C-mutant colon cancer, and prostate cancer. HFB200901 disrupts the LGALS9/TIM-3 axis, while blocking the internalization and vacuolization of recombinant LGALS9. HFB200901 reduces the proportion of regulatory T cells (Treg) and enhances dendritic cell activation, thereby inducing polyfunctional and memory CD8+ T cell responses. HFB200901 inhibits the progression of pancreatic neoplastic lesions and effectively improves the efficacy of PSMA-based vaccination.
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TIM-3-ligand-1
0 ImagesCat. No.: HY-171537CAS No.: 2883237-01-0TIM-3-ligand-1 (Compound 35) is a highly efficient and selective TIM-3 ligand with a Ki value of 156 nM. TIM-3-ligand-1 can be used for research in immunotherapy.
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Apotracker Red
0 ImagesCat. No.: HY-D2972CAS No.: 2889374-63-2Apotracker Red is a fluorogenic peptide (excitation/emission: 561/610 nm). Apotracker Red binds to PtdSer on the surface of cells. Apotracker Red rapidly and selectively stains Apoptotic cells but not viable cells. Apotracker Red can be used to detect cancer cell death in real time.
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TQB2618
0 ImagesCat. No.: HY-P991395TQB2618 is a human IgG4 monoclonal antibody (mAb) targeting TIM-3/HAVCR2/CD366. TQB2618 activates immune cell function and induces significant anti-tumor activity when used in combination with anti-PD-1 agents.
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