2. Signaling Pathways
  3. Immunology/Inflammation
  4. LILRB
  5. LILRB4 Isoform
  6. LILRB4 Inhibitor

LILRB4 Inhibitor

LILRB4 Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-P990092
    Rolistobart
    		Inhibitor
    Rolistobart is a humanized immunoglobulin G4-kappa, anti-LILRB4/CD85k monoclonal antibody. Rolistobart is an immunostimulant and antineoplastic.
  • HY-P991308
    TRX385
    		Inhibitor
    TRX385 is a human monoclonal antibody (mAb) targeting LILRB4/ILT3/CD85k. TRX385 can be used in anticancer and antiviral research.
  • HY-P991307
    BND-35
    		Inhibitor
    BND-35 is a human monoclonal antibody (mAb) targeting LILRB4/ILT3/CD85k. BND-35 blocks the interaction of ILT3 with APOE and fibronectin, enhances the pro-inflammatory activity of various myeloid cells, and reverses ILT3-mediated immunosuppression of T cells by various suppressive myeloid cells. BND-35 has anti-tumor activity in the hILT3 transgenic mouse tumor model.