CD16B Antibody (YA7117)
CD16B Antibody (YA7117) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD16B.
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Host:
Mouse
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Isotype:
IgG1
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Application:
FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
Applications
| Application |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:400 | 1:10000 |
Product Details
CD16B Antibody (YA7117) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD16B.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 26.2kDa;
SwissProt: SwissProt: O75015
Purified recombinant fragment of human CD16B (AA: 17-200) expressed in E. Coli.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD16B receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils
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Subcellular Localization
Cell membrane,Secreted
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Expression
Tissue_Specificity: Expressed specifically by polymorphonuclear leukocytes (neutrophils). Also expressed by stimulated eosinophils -
Isoforms & Post-Translational Modification
O75015: 233 amino acids, molecular weight 26243 Da.
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Subunit
Monomer
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SwissProt ID
Documentation