G0S2 Antibody
(Synonyms: G0/G1 switch protein 2, G0/G1 switch regulatory protein 2, Putative lymphocyte G0/G1 switch gene, G0S2)G0S2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to G0S2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 |
Product Details
G0S2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to G0S2.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 11 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 11 kDa
Synthetic peptide of human G0S2.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
G0S2 promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers
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Subcellular Localization
Mitochondrion
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Expression
Tissue_Specificity: Widely expressed with highest levels in peripheral blood, skeletal muscle and heart, followed by kidney and liver.
Induction: Induced by TNF through the activation of the NFKB pathway. -
Isoforms & Post-Translational Modification
G0S2 has an amino acid length of 103, molecular weight is 11321 Da.
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Subunit
Directly interacts with BCL2; this interaction prevents the formation of the anti-apoptotic BAX-BCL2 complex
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SwissProt ID
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Synonyms
G0/G1 switch protein 2, G0/G1 switch regulatory protein 2, Putative lymphocyte G0/G1 switch gene, G0S2
Documentation
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