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Art. -Nr.: HY-132065

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Decaethylene glycol dodecyl ether

(Synonyms: PEG10-dodecyl)

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Decaethylene glycol dodecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

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Reinheit: 99.91%
CAS. Nr.: 618113-48-7
Formel: C₃₂H₆₆O₁₁
Molecular Weight:626.86

Speicherung:

Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Decaethylene glycol dodecyl ether Chemical Structure

CAS. Nr.: 618113-48-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Bioz

Biologische Aktivität

Beschreibung

Decaethylene glycol dodecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

Alle PROTAC Linkers Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
MOLT-4	IC₅₀	26 μM Compound: HL-10	Growth inhibition of HIV1 3B infected human MOLT4 cells after 5 days by MTT assay Growth inhibition of HIV1 3B infected human MOLT4 cells after 5 days by MTT assay	[PMID: 18672367]
MOLT-4	IC₅₀	41 μM Compound: HL-10	Growth inhibition of human MOLT4 cells after 5 days by MTT assay Growth inhibition of human MOLT4 cells after 5 days by MTT assay	[PMID: 18672367]

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 618113-48-7
Appearance Oil
Molecular Weight 626.86
Formel C₃₂H₆₆O₁₁
Color White to off-white
SMILES

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
Synonyms

PEG10-dodecyl
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Reinheit & Dokumentation

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Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass

Konzentration

Volumen

Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Decaethylene glycol dodecyl ether

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Biologische Aktivität
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- IC50 & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
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Decaethylene glycol dodecyl ether

Alle PROTAC Linkers Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Decaethylene glycol dodecyl ether Related Classifications

Art. -Nr.: HY-132065