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Art. -Nr.: HY-185455

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FEN1-IN-9

FEN1-IN-9 is a selective flap endonuclease 1 (FEN1) inhibitor with an IC₅₀ of 37.9 μM. FEN1-IN-9 can be used for the research of DNA damage repair.

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CAS. Nr.: 758720-87-5
Formel: C₁₀H₆Cl₂O₄
Molecular Weight:261.06

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

FEN1-IN-9 Chemical Structure

CAS. Nr.: 758720-87-5

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

FEN1-IN-9 is a selective flap endonuclease 1 (FEN1) inhibitor with an IC₅₀ of 37.9 μM. FEN1-IN-9 can be used for the research of DNA damage repair^[1].

IC₅₀ & Target^[1]

FEN1

37.9 μM (IC₅₀)

In Vitro

FEN1-IN-9 (Compound 12) inhibits purified FEN1 with an IC₅₀ of 37.9 μM and shows selectivity over purified XPG (IC₅₀ >100 μM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 758720-87-5
Molecular Weight 261.06
Formel C₁₀H₆Cl₂O₄
SMILES

O=C(C(CC(C1=C(Cl)C=CC=C1Cl)=O)=O)O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Tumey LN, et al. The identification and optimization of 2,4-diketobutyric acids as flap endonuclease 1 inhibitors. Bioorg Med Chem Lett. 2004;14(19):4915-4918. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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