LRRC25 - leucine rich repeat containing 25 Gene

Also Known as MAPA

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 126364

About LRRC25

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:18,391,137-18,397,622 (from NCBI)

This gene has 2 transcripts (splice variants) and 82 orthologues. Broad expression in spleen (RPKM 16.6), bone marrow (RPKM 11.9) and 16 other tissues.

Summary

Predicted to be located in cytoplasm. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

LRRC25 Products (1)

mRNA Protein Name
NM_145256.3 NP_660299.2 leucine-rich repeat-containing protein 25 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
21044950 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LRRC25 Protein Structure

LRR_4

LRR_4: Leucine Rich repeats (2 copies) (64 - 101)

  • 0
  • 100
  • 200
  • 305 a.a.
Protein Preferred Names Protein Names

leucine-rich repeat-containing protein 25

  • monocyte and plasmacytoid activated molecule

LRRC25 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
LRRC25 Q8N386 CLEC1A Homo sapiens Q8NC01
Validated Y2H
32296183
Intra
LRRC25 Q8N386 CNIH3 Homo sapiens Q8TBE1
Validated Y2H
32296183
Intra
LRRC25 Q8N386 CLDN19 Homo sapiens Q8N6F1-2
Validated Y2H
32296183
Intra
LRRC25 Q8N386 PKMYT1 Homo sapiens Q99640-2
Validated Y2H
32296183
Intra
LRRC25 Q8N386 GPRC5D Homo sapiens Q9NZD1
Validated Y2H
32296183
Intra
LRRC25 Q8N386 AGPAT4 Homo sapiens Q9NRZ5
Validated Y2H
32296183
Intra
LRRC25 Q8N386 LHFPL5 Homo sapiens Q8TAF8
Validated Y2H
32296183
Intra
LRRC25 Q8N386 FAM3C Homo sapiens Q92520
Validated Y2H
32296183
Intra
LRRC25 Q8N386 CLN6 Homo sapiens Q9NWW5
Validated Y2H
32296183
Intra
LRRC25 Q8N386 ACD Homo sapiens Q96AP0
Pull Down
21044950
Intra
LRRC25 Q8N386 ACD Homo sapiens Q96AP0
BiFC
21044950
Intra
LRRC25 Q8N386 TMEM120A Homo sapiens Q9BXJ8
Validated Y2H
32296183
Intra
LRRC25 Q8N386 FATE1 Homo sapiens Q969F0
Validated Y2H
32296183
Intra
LRRC25 Q8N386 FATE1 Homo sapiens Q969F0
Y2H Array
32296183
Intra
LRRC25 Q8N386 FATE1 Homo sapiens Q969F0
Y2H Prey Pooling
32296183
Intra
LRRC25 Q8N386 YIPF6 Homo sapiens Q96EC8
Validated Y2H
32296183
Intra
LRRC25 Q8N386 TRAF3IP3 Homo sapiens Q9Y228
Validated Y2H
32296183
Intra
LRRC25 Q8N386 DNAJC30 Homo sapiens Q96LL9
Validated Y2H
32296183
Intra
LRRC25 Q8N386 SMCO4 Homo sapiens Q9NRQ5
Validated Y2H
32296183
Intra
LRRC25 Q8N386 SEC22A Homo sapiens Q96IW7
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant LRRC25 Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P70876 LRRC25 Protein, Human (HEK293, His) Q8N386 (L21-T165) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Campylobacteriosis

  • Campylobacter Infections

  • Campylobacter Infection

  • Enteric Campylobacteriosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS07812 LRRC25 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20564 Lrrc25 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27073 Lrrc25 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta LRRC25 VGNC VGNC:74401
Bos taurus LRRC25 VGNC VGNC:31006
Canis familiaris LRRC25 VGNC VGNC:42791
Rattus norvegicus LRRC25 RGD RGD:1564818
Felis catus LRRC25 VGNC VGNC:63292
Mus musculus LRRC25 MGD MGI:2445284
Others LRRC25 NCBI