CLEC-1
CLEC-1, encoded by CLEC1A, is a type II transmembrane C-type lectin receptor expressed predominantly on dendritic cells. Situated within the DNGR/CLEC-2 subgroup of the C-type lectin superfamily, it pairs a short cytoplasmic tail with a single extracellular carbohydrate-recognition domain. Its cytoplasmic region contains an ITIM-like motif, hinting at inhibitory or immunomodulatory signaling, yet its physiological ligand remains poorly defined. Expression is largely restricted to myeloid and plasmacytoid dendritic-cell populations, suggesting a role in tuning adaptive-immune priming. Recombinant CLEC-1 protein serves studies of dendritic-cell biology and lectin-receptor signaling within this less-characterized branch of the receptor family.
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CLEC-1 Recombinant Proteins (3)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
