1. Recombinant Proteins
  2. Receptor Proteins
  3. Pattern Recognition Receptors
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  5. CLEC-1
  6. CLEC-1/CLEC1A Protein, Rat (HEK293, Fc)

CLEC-1/CLEC1A Protein, Rat (HEK293, Fc)

Cat. No.: HY-P75337
Handling Instructions

CLEC-1/CLEC1A proteins belong to the CTL/CTLD superfamily and are known for their diverse functions in cell adhesion, signaling, glycoprotein turnover, inflammation, and immune responses. It is involved in potentially regulating dendritic cell function. CLEC-1/CLEC1A Protein, Rat (HEK293, Fc) is the recombinant rat-derived CLEC-1/CLEC1A protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CLEC-1/CLEC1A Protein, Rat (HEK293, Fc) is 197 a.a., with molecular weight of ~51.6 kDa.

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Description

CLEC-1/CLEC1A proteins belong to the CTL/CTLD superfamily and are known for their diverse functions in cell adhesion, signaling, glycoprotein turnover, inflammation, and immune responses. It is involved in potentially regulating dendritic cell function. CLEC-1/CLEC1A Protein, Rat (HEK293, Fc) is the recombinant rat-derived CLEC-1/CLEC1A protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CLEC-1/CLEC1A Protein, Rat (HEK293, Fc) is 197 a.a., with molecular weight of ~51.6 kDa.

Background

The C-type lectin-like domain-containing protein 1 (CLEC1A) is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily, known for its diverse functions, including cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. This protein is implicated in the potential regulation of dendritic cell function. Situated on chromosome 12p13 in the natural killer gene complex region, CLEC1A is closely linked to other members of the CTL/CTLD superfamily. Alternative splicing gives rise to multiple transcript variants, contributing to the functional diversity of this gene. With biased expression observed in placenta (RPKM 18.1), lung (RPKM 3.8), and 10 other tissues, CLEC1A underscores its potential role in various physiological contexts.

Species

Rat

Source

HEK293

Tag

N-hFc

Accession

D3ZGU3 (Q73-Q269)

Gene ID

500337  [NCBI]

Molecular Construction
N-term
hFc
CLEC-1 (Q73-Q269)
Accession # D3ZGU3
C-term
Synonyms
CLEC1A; C-type lectin domain family 1 member A; CLEC1
Molecular Weight

Approximately 51.6 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

CLEC-1/CLEC1A Protein, Rat (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CLEC-1/CLEC1A Protein, Rat (HEK293, Fc)
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HY-P75337
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