L-748328
L-748328 is a potent and selective human β3-adrenergic receptor antagonist. L-748328 has a Ki of 3.7 nM against human cloned β3-AR expressed in Chinese hamster ovary (CHO) cells. In addition, L-748328 inhibits the lipolytic response induced by the β3-AR agonist L-742791 in isolated non-human primate adipocytes.
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- CAS. Nr.: 244192-93-6
- Formel: C23H27N3O6S2
- Molecular Weight:505.61
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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β3 adrenoceptor 3.7 nM (Ki) |
Chemical Information
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CAS. Nr. 244192-93-6
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Molecular Weight 505.61
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Formel C23H27N3O6S2
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SMILES
O=S(C1=CC=CC(OC[C@H](CNCCC2=CC=C(C=C2)NS(=O)(C3=CC=CC=C3)=O)O)=C1)(N)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
L-748328 Related Classifications
HY-118944 Related Classifications
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