Imidazenil
Based on 1 Customer Validation
Imidazenil is a partial positive allosteric modulator of GABAA receptors with anxiolytic, antipanic and anticonvulsant activities.
For research use only. We do not sell to patients.
- Purity: 98.95%
- CAS No.: 151271-08-8
- Formula: C18H12BrFN4O
- Molecular Weight:399.22
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 151271-08-8
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Appearance Solid
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Molecular Weight 399.22
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Formula C18H12BrFN4O
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Color White to off-white
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SMILES
O=C(C1=C2CN=C(C3=C(Br)C=CC=C3)C4=C(C=CC(F)=C4)N2C=N1)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (125.24 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Giusti P, Ducić I, Puia G, et al. Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors. J Pharmacol Exp Ther. 1993;266(2):1018-1028. [Content Brief]
[2]. Thompson DM, Auta J, Guidotti A, Costa E. Imidazenil, a new anxiolytic and anticonvulsant drug, attenuates a benzodiazepine-induced cognition deficit in monkeys. J Pharmacol Exp Ther. 1995;273(3):1307-1312. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.5049 mL | 12.5244 mL | 25.0488 mL | 62.6221 mL |
| 5 mM | 0.5010 mL | 2.5049 mL | 5.0098 mL | 12.5244 mL | |
| 10 mM | 0.2505 mL | 1.2524 mL | 2.5049 mL | 6.2622 mL | |
| 15 mM | 0.1670 mL | 0.8350 mL | 1.6699 mL | 4.1748 mL | |
| 20 mM | 0.1252 mL | 0.6262 mL | 1.2524 mL | 3.1311 mL | |
| 25 mM | 0.1002 mL | 0.5010 mL | 1.0020 mL | 2.5049 mL | |
| 30 mM | 0.0835 mL | 0.4175 mL | 0.8350 mL | 2.0874 mL | |
| 40 mM | 0.0626 mL | 0.3131 mL | 0.6262 mL | 1.5656 mL | |
| 50 mM | 0.0501 mL | 0.2505 mL | 0.5010 mL | 1.2524 mL | |
| 60 mM | 0.0417 mL | 0.2087 mL | 0.4175 mL | 1.0437 mL | |
| 80 mM | 0.0313 mL | 0.1566 mL | 0.3131 mL | 0.7828 mL | |
| 100 mM | 0.0250 mL | 0.1252 mL | 0.2505 mL | 0.6262 mL |
Imidazenil Related Classifications
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