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atx-002

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5

Inhibitors & Agonists

2

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99810
    Quisovalimab

    AVTX-002; AEVI 002; SAR 252067; CERC-002; MDGN-002

    		 SARS-CoV Infection Inflammation/Immunology
    Quisovalimab (AVTX-002) is a human-derived monoclonal antibody against LIGHT (TNFSF14). Quisovalimab binds to LIGHT, blocks the signal transduction activity of LIGHT, reduces circulating LIGHT levels and attenuates pro-inflammatory effects. Quisovalimab can be used in research related to Crohn's disease, COVID-19-associated pneumonia and acute respiratory distress syndrome comorbidity .
    Quisovalimab
  • HY-139558
    Zapnometinib

    PD0184264; ATR-002

    		 MEK Influenza Virus Bacterial Infection Cancer
    Zapnometinib (PD0184264), an active metabolite of CI-1040, is a MEK inhibitor, with an IC50 of 5.7 nM. Zapnometinib exhibits antiviral activity against influenza virus and antibacterial activities .
    Zapnometinib
  • HY-160207
    Elunetirom

    MA-JD21; ABX-002

    		 Thyroid Hormone Receptor Neurological Disease
    Elunetirom (MA-JD21 )is a TR-β selective CNS-penetrant TR-β agonist prodrug and can be used for study of major depressive disorder (MDD) .
    Elunetirom
  • HY-P991351
    RTX-002

    		PD-1/PD-L1 Inflammation/Immunology
    RTX-002 is a human monoclonal antibody (mAb) targeting PDCD1/PD-1/CD279. RTX-002 can be used to study autoimmune diseases such as systemic lupus erythematosus and multiple sclerosis .
    RTX-002
  • HY-183001
    ATX-012

    		Liposome CFTR Inflammation/Immunology
    ATX-012 is an ionizable cationic lipid. ATX-012 can be used to prepare lipid formulations that encapsulate CFTR mRNA. ATX-012 is applicable to research related to cystic fibrosis .
    ATX-012

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