Angiotensin II

Deborah L. Morris  1 ,  Devang Sanghavi  2 ,  Chadi I. Kahwaji  3
Affiliations
  • 1. Methodist Un Physician Assistant Program
  • 2. Mayo Clinic
  • 3. Universtity of California, Irvine
PMID: 29763087
Abstract

Angiotensin is a peptide endocrine hormone and an important part of the renin-angiotensin-aldosterone system, an inter-related endocrine system important in volume and blood pressure control. Angiotensinogen, an alpha-globulin, and the peptide prohormone is synthesized primarily by the liver and circulates in plasma. Angiotensin II (AT-II) has recently received FDA approval for use in patients in shock. This activity reviews the indications, contraindications, activity, adverse events, and Other key elements of AT-II therapy in the clinical setting as relates to the essential points needed by members of an interprofessional team managing the care of patients presenting with shock.