Sarmentogenin
Sarmentogenin is a cardenolide aglycone can be found in rhodexin A and Chrysolina herbacea.
For research use only. We do not sell to patients.
- CAS No.: 76-28-8
- Formula: C23H34O5
- Molecular Weight:390.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | Inhibition |
105.751 %
Compound: SARMENTOGENIN
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Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
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[PMID: 23571415] |
| CHO | Inhibition |
70.5845 %
Compound: SARMENTOGENIN
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Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
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[PMID: 23571415] |
| HCT-116 | Survival |
26 %
Compound: sarmentogenin
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Cytotoxicity against human HCT116 cells assessed as survival index at 10 uM after 72 hrs by FMCA method
Cytotoxicity against human HCT116 cells assessed as survival index at 10 uM after 72 hrs by FMCA method
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[PMID: 19894733] |
| HT-29 | Survival |
63 %
Compound: sarmentogenin
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Cytotoxicity against human HT-29 cells assessed as survival index at 10 uM after 72 hrs by FMCA method
Cytotoxicity against human HT-29 cells assessed as survival index at 10 uM after 72 hrs by FMCA method
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[PMID: 19894733] |
Chemical Information
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CAS No. 76-28-8
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Molecular Weight 390.51
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Formula C23H34O5
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SMILES
C[C@@]12[C@@]([C@@]3([H])[C@]([C@@]4([C@](C[C@H](CC4)O)([H])CC3)C)([H])[C@@H](C1)O)(CC[C@@H]2C(CO5)=CC5=O)O
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Structure Classification
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Initial Source
Chrysolina herbacea
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Song F, et al. Chemoenzymatic synthesis of the cardenolide rhodexin A and its aglycone sarmentogenin. Beilstein J Org Chem. 2025;21:2637-2644. Published 2025 Dec 3. [Content Brief]
[2]. Pasteels JM, et al. Cardiac glycosides in the defensive secretion of Chrysolina herbacea (Coleoptera, Chrysomelidae). Identification, biological role and pharmacological activity. Comp Biochem Physiol C Comp Pharmacol. 1979;63C(1):117-21. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sarmentogenin Related Classifications
HY-N14147 Related Classifications
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